NCT04304170 is a NA clinical trial of VES002 in Constipation, sponsored by CEN Biotech.

Who is sponsoring NCT04304170?

NCT04304170 is sponsored by CEN Biotech.

What drugs are being tested in NCT04304170?

Interventions in NCT04304170: VES002, Placebo.

What condition does NCT04304170 study?

NCT04304170 studies Constipation.

Is NCT04304170 still recruiting?

NCT04304170 is currently completed. Last updated 11 March 2020.

Last reviewed 2020-03-11 · How we verify

NCT04304170

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Dietary Supplementation Effects on Bowel Movement Frequency and Intestinal Biological Markers in Seniors Presenting Slowed Intestinal Transit

Completed NA Last updated 11 March 2020

What this trial tests

NA trial testing VES002 in Constipation in 27 participants. Completed in 15 March 2018.

Timeline

21 February 2017

Primary endpoint
15 March 2018

15 March 2018

Quick facts

Lead sponsor	CEN Biotech
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	27
Start date	21 February 2017
Primary completion	15 March 2018
Estimated completion	15 March 2018
Sites	1 location across France

Drugs / interventions tested

VES002
Placebo

Conditions studied

Constipation — all drugs for Constipation →

Sponsor

CEN Biotech — full company profile →

Who can join

Adults 50 to 70, any sex, with Constipation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This randomized, double-blind, controlled clinical trial among healthy volunteers with infrequent bowel movements but not severe constipation evaluate the effects of a supplementation in "symbiotic" on intestinal transit of subjects with few bowel movements per week with a verum group treated with a dietary supplement composed of fructo-oligosaccharides - FOS: 4.95 gr / sachet and Bifidobacterium animalis lactis: VES002 (LMG P-28149): 5 billion / sachet and a placebo group treated with a comparative product hat looked strictly identical to the verum and contained only excipients (60% maltodextrin / 40% sucrose). The claim investigated corresponds to the section of the new EFSA (European Food Safety Authority) guidance of 2016 entitled "Claims on maintenance of normal defecation".

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Gut Microbiome-Brain Alliance: A Landscape View into Mental and Gastrointestinal Health and Disorders.
Sasso JM, Ammar RM, Tenchov R, Lemmel S, et al · · 2023 · cited 100× · PMID 37156006 · DOI 10.1021/acschemneuro.3c00127

Verify or expand the search:

Other recruiting trials for Constipation

Currently open trials in the same condition.

NCT07462481 — Probiotic Improve Constipation · NA · recruiting
NCT07466914 — Constipation in Children With Cerebral Palsy · active not recruiting
NCT07215351 — Impact of the Inno Cleanse Dietary Supplement on Gut Health and Associated Variables in Healthy Men and Women · NA · recruiting
NCT07135362 — The Efficacy Evaluation of TCI604 Probiotic on Intestinal Function Improvement · NA · recruiting
NCT07091084 — A Study of Herbal Supplements in Cancer Survivors With Constipation · NA · recruiting

Other CEN Biotech trials

Trials by the same sponsor.

NCT07370480 — Knee Osteoarthritis and Thermal Spa Treatment · NA · recruiting
NCT07295678 — URGO FilmoCream Eczema + Dermocorticoids in Atopic Dermatitis · NA · not yet recruiting
NCT06617975 — Knee Osteoarthritis and Spa Therapy · NA · recruiting
NCT06278324 — Effectiveness of a Nasal Spray on Viral Respiratory Infections · NA · completed
NCT06054737 — Chronic Venous Insufficiency and Balneotherapy · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04304170 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by CEN Biotech
Last refreshed: 11 March 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04304170.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing