NCT04302532 is a Phase 4 clinical trial of Coenzyme Q10 in Coenzyme q10, sponsored by Karachi Medical and Dental College.

Who is sponsoring NCT04302532?

NCT04302532 is sponsored by Karachi Medical and Dental College.

What drugs are being tested in NCT04302532?

Interventions in NCT04302532: Coenzyme Q10, clomiphene citrate.

What condition does NCT04302532 study?

NCT04302532 studies Coenzyme q10.

Is NCT04302532 still recruiting?

NCT04302532 is currently completed. Last updated 25 November 2020.

Last reviewed 2020-11-25 · How we verify

NCT04302532

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Coenzyme q 10 and Fertility Outcome in Women With Clomiphene Resistant PCOS

Completed Phase 4 Last updated 25 November 2020

What this trial tests

Phase 4 trial testing Coenzyme Q10 in Coenzyme q10 in 149 participants. Completed in 30 October 2020.

Timeline

1 July 2020

Primary endpoint
30 September 2020

30 October 2020

Quick facts

Lead sponsor	Karachi Medical and Dental College
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	149
Start date	1 July 2020
Primary completion	30 September 2020
Estimated completion	30 October 2020
Sites	1 location across Pakistan

Drugs / interventions tested

Coenzyme Q10 — full drug profile →
clomiphene citrate — full drug profile →

Conditions studied

Coenzyme q10 — all drugs for Coenzyme q10 →

Sponsor

Karachi Medical and Dental College

Who can join

Adults 20 to 35, female only, with Coenzyme q10. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study evaluates the effect of coenzyme q 10 on ovulation and subsequent pregnancy in women with polycystic ovarian syndrome. Half of the participants will receive coq10 and ovulation induction with clomiphene and other half would receive a placebo with clomiphene.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Ovarian Aging: Mechanisms, Age-Related Disorders, and Therapeutic Interventions.
Liu X, Zhao Y, Feng Y, Wang S, et al · · 2025 · cited 3× · PMID 41256733 · DOI 10.1002/mco2.70481
Effect of Administrating Coenzyme Q10 with Clomiphene Citrate on Ovulation Induction in Polycystic Ovary Syndrome Cases with Resistance to Clomiphene Citrate: A Randomized Controlled Trial.
Izhar R, Husain S, Tahir MA, Husain S. · · 2022 · cited 3× · PMID 36415489 · DOI 10.18502/jri.v23i3.10008

Verify or expand the search:

Other trials of Coenzyme Q10

Trials testing the same drug.

NCT06743802 — The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery · Phase 4 · recruiting
NCT06856447 — The Role of Coenzyme Q10 in the Prophylaxis of Oxaliplatin Induced Peripheral Neuropathy in Patients With Colorectal Can · Phase 1 · recruiting
NCT07096557 — The Effect of Co-enzyme Q10 on the Clinical Outcome of Pediatric Patients With Systemic Lupus Erythematosus · Phase 2 · completed
NCT06040905 — Causal Effect of Coenzyme Q10 Nutrition and Cognitive Dysfunction in the Metabolic Storm (Hyperglycemia and Sarcopenia) · NA · recruiting
NCT05873673 — Coenzyme Q10 and Dentoalveolar Cyst · Phase 2 · active not recruiting

Other Karachi Medical and Dental College trials

Trials by the same sponsor.

NCT04452968 — Comparison of Intermittent Fasting and Caloric Deficit for Weight Loss in Women With Polycystic Ovarian Syndrome · NA · completed
NCT02762097 — Clinical Pregnancy Rate After Removal of Unsuspected Polyps · Phase 3 · withdrawn
NCT04436172 — Spinal Anesthesia Facilitated Sexual Intercourse As A Treatment Option For Vaginismus · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04302532 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Karachi Medical and Dental College
Last refreshed: 25 November 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04302532.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing