Last reviewed · How we verify
Coenzyme Q10
Coenzyme Q10 (CoQ10) is a naturally occurring compound that plays a crucial role in cellular energy production. It is widely used as a dietary supplement and has been studied for its potential benefits in various health conditions, including cardiovascular diseases, neurodegenerative disorders, and mitochondrial disorders. Despite its widespread use, CoQ10 has not received FDA approval for any specific indication. The safety profile of CoQ10 is generally favorable, with few reported side effects. However, it may interact with certain medications, particularly blood thinners. Research on CoQ10 continues to explore its therapeutic potential and safety in different populations.
At a glance
| Generic name | Coenzyme Q10 |
|---|---|
| Also known as | ubiquinone, Coenzyme Q10 Forte, CoQ, Ubiquinone, CC 100 mg/day 2-6 and CoQ10,60 mg 3 times day orally on day 2 till hCG |
| Sponsor | Nanjing Medical University |
| Drug class | Dietary supplement |
| Target | Mitochondrial electron transport chain |
| Modality | Small molecule |
| Therapeutic area | Neuroscience |
| Phase | FDA-approved |
Approved indications
Pipeline indications
Common side effects
Drug interactions
- Warfarin (may reduce anticoagulant effect)
- Chemotherapy drugs (potential interaction)
Key clinical trials
- Renoprotective Role of Vitamin C and Coenzyme Q10 in Nephrotoxicity (PHASE2, PHASE3)
- The Effect of Co-enzyme Q10 on the Clinical Outcome of Pediatric Patients With Systemic Lupus Erythematosus (PHASE2)
- Alpha Lipoic Acid Plus Coenzyme Q10 Versus Coenzyme Q10 Alone in Asthenozoospermia (NA)
- Comparing the Effects of Commercially Available Dietary Supplements on CoQ10 Concentrations (PHASE2, PHASE3)
- Effectiveness of Coenzyme Q10 and Probiotics in Periodontal Therapy During Pregnancy (NA)
- Coenzyme Q10 for Neuroprotection in Paclitaxel-Induced Neuropathy (PHASE2)
- North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
- Alii Supplement Study (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |