NCT04294056 is a Phase 1 clinical trial of Ciprofol in Anesthesia, sponsored by Haisco Pharmaceutical Group Co., Ltd..

Who is sponsoring NCT04294056?

NCT04294056 is sponsored by Haisco Pharmaceutical Group Co., Ltd..

What drugs are being tested in NCT04294056?

Interventions in NCT04294056: Ciprofol, Propofol.

What condition does NCT04294056 study?

NCT04294056 studies Anesthesia.

Is NCT04294056 still recruiting?

NCT04294056 is currently completed. Last updated 20 November 2020.

Last reviewed 2020-11-20 · How we verify

NCT04294056

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Study to Evaluate the Differences in Pharmadynamics, Pharmacokinetics, and Safety Between Ciprofol and Propofol

Completed Phase 1 Last updated 20 November 2020

What this trial tests

Phase 1 trial testing Ciprofol in Anesthesia in 18 participants. Completed in 18 September 2020.

Timeline

26 May 2020

Primary endpoint
22 June 2020

18 September 2020

Quick facts

Lead sponsor	Haisco Pharmaceutical Group Co., Ltd.
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	treatment
Enrollment	18
Start date	26 May 2020
Primary completion	22 June 2020
Estimated completion	18 September 2020
Sites	1 location across China

Drugs / interventions tested

Ciprofol — full drug profile →
Propofol (Propofol) — full drug profile →

Conditions studied

Anesthesia — all drugs for Anesthesia →

Sponsor

Haisco Pharmaceutical Group Co., Ltd. — full company profile →

Who can join

Adults 18 to 45, male only, with Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a single-center, open-label, randomized, two-stage, two-way crossover Phase I study in healthy male subjects.The main objective is to evaluate the differences in pharmadynamics (PD), pharmacokinetics (PK), and safety between ciprofol injectable emulsion and propofol injectable emulsion at different doses in healthy subjects.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effects of Cipepofol on Cardiac Depolarization and Repolarization in Healthy Subjects: A Single-Center, Randomized, Placebo and Positive-Controlled Thorough QT Study.
Kleiman R, Rudo T, Daley W, Hu M, et al · · 2026 · PMID 41858914 · DOI 10.2147/dddt.s565051

Verify or expand the search:

Other trials of Ciprofol

Trials testing the same drug.

NCT07376577 — Efficacy and Safety of Anricofen Combined With Ciprofol for Deep Sedation in Elderly Patients Undergoing ERCP · NA · not yet recruiting
NCT07294989 — The Effective Blood Concentration of Ciprofol · recruiting
NCT06934811 — Ciprofol's Impact on Oxygenator Function in Extracorporeal Membrane Oxygenation (ECMO) Patients · Phase 4 · not yet recruiting
NCT06735430 — Ciprofol Based on Total Intravenous Anesthesia During Pediatric Laparoscopic Surgery · NA · completed
NCT06674226 — Effects of Ciprofol on Postoperative Delirium and Outcomes in Elderly Patients Undergoing Major Thoracic Surgery · Phase 4 · recruiting

Other recruiting trials for Anesthesia

Currently open trials in the same condition.

NCT07294092 — Ketamine and Propofol NeuroImaging · EARLY_PHASE1 · recruiting
NCT07290205 — Remimazolam NeuroImaging · EARLY_PHASE1 · recruiting
NCT07465185 — Intrathecal Bupivacaine With or Without Dexmetomidine for Cesserian Delivery · Phase 2 · recruiting
NCT07269808 — Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration · Phase 3 · recruiting
NCT07443254 — Prospective IR-led Sedation Feasibility · Phase 1, PHASE2 · recruiting

Other Haisco Pharmaceutical Group Co., Ltd. trials

Trials by the same sponsor.

NCT07533786 — A Clinical Trial Evaluating the Efficacy and Safety of HSK55718 in Patients for Postoperative Pain Treatment in Abdomina · Phase 2 · not yet recruiting
NCT07519070 — A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of HSK44 · Phase 3 · not yet recruiting
NCT07503587 — Evaluating the Efficacy and Safety of of HSK44459 in People With Progressive Pulmonary Fibrosis · Phase 3 · not yet recruiting
NCT07521345 — A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and the Food Effect of HSK55879 Tablets in Healt · Phase 1 · recruiting
NCT07335055 — A Study for HSK47388 in Participants With Ulcerative Colitis · Phase 2 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04294056 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Haisco Pharmaceutical Group Co., Ltd.
Last refreshed: 20 November 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04294056.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing