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NCT04287998
Role and Expression of MXRA5 in Placental Connective Tissue Remodelling in Preeclampsia
trial in Pre-Eclampsia in 50 participants. Status unknown.
1 April 2021
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 April 2020 |
| Primary completion | 1 April 2021 |
| Estimated completion | 1 May 2021 |
Conditions studied
- Pre-Eclampsia — all drugs for Pre-Eclampsia →
Sponsor
Assiut University
Who can join
Adults 20 to 40, female only, with Pre-Eclampsia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
1. To measure the level of expression of MXRA5 and ANXA4 genes in preeclampsia (PE). 2. To detect the effect of heavy metals (lead (Pb) and arsenic (AR)) on these two genes in the pathology of PE. 3. To explore the association of the previous two genes with the heavy metals in link with Phosphoinositide 3-kinases/Protein Kinase B (PI3K/AKT) pathway. 4. To detect Syndecan-1 by immunohistochemical antibodies. 5. To define the role of extracellular matrix remodelling in PE.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04287998
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Pre-Eclampsia
Currently open trials in the same condition.
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- NCT06893510 — Virtual Reality-Based and Face-to-Face Relaxation Programs in Pregnant Women With Preeclampsia · NA · recruiting
- NCT06122220 — Optic Nerve Sheath Measurement and Angiogenic Factors in Patients With Pre-eclampsia. · NA · recruiting
- NCT06779916 — Autophagy/Apoptosis Balance in Placental Vascular Pathologies · recruiting
Other Assiut University trials
Trials by the same sponsor.
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- NCT07194863 — Efficacy of Essential Phospholipid Versus Betaine HCL/L-Glutamic Acid in MAFLD · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04287998 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 27 February 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04287998.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing