NCT04286555 (DASH4D) is a NA clinical trial of DASH4D diet in Diabetes Mellitus, Type 2, sponsored by Johns Hopkins University.

Who is sponsoring NCT04286555?

NCT04286555 is sponsored by Johns Hopkins University.

What drugs are being tested in NCT04286555?

Interventions in NCT04286555: DASH4D diet, comparison diet, higher sodium, lower sodium.

What condition does NCT04286555 study?

NCT04286555 studies Diabetes Mellitus, Type 2, Diabetes, Diabetes type2, Type2 Diabetes, Type 2 Diabetes, Type II Diabetes, Hypertension, High Blood Pressure.

Is NCT04286555 still recruiting?

NCT04286555 is currently completed. Last updated 20 November 2024.

Last reviewed 2024-11-20 · How we verify

NCT04286555: DASH4D

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Dietary Approaches to Stop Hypertension for Diabetes

Completed NA Last updated 20 November 2024

What this trial tests

NA trial testing DASH4D diet in Diabetes Mellitus, Type 2 in 105 participants. Completed in 17 June 2024.

Timeline

2 June 2021

Primary endpoint
13 June 2024

17 June 2024

Quick facts

Lead sponsor	Johns Hopkins University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	105
Start date	2 June 2021
Primary completion	13 June 2024
Estimated completion	17 June 2024
Sites	1 location across United States

Drugs / interventions tested

DASH4D diet
comparison diet
higher sodium
lower sodium

Conditions studied

Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →
Diabetes — all drugs for Diabetes →
Diabetes type2 — all drugs for Diabetes type2 →
Type2 Diabetes — all drugs for Type2 Diabetes →

Sponsor

Johns Hopkins University

Who can join

18 and older, any sex, with Diabetes Mellitus, Type 2 or Diabetes. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of the DASH4D trial is to determine the effects, alone and combined, of (a) the DASH4D diet (a DASH-style diet modified for people with diabetes) vs. comparison diet that is typical of what many Americans with diabetes eat and (b) lower sodium intake vs. higher sodium intake on blood pressure (BP). The core design is a single-site, 4-period, crossover feeding study with 5-week periods. Participants are fed each of four isocaloric diets, presented in random order. The primary contrast of interest is DASH4D diet with lower sodium vs. comparison diet with higher sodium.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Dietary Patterns, Sodium Reduction, and Blood Pressure in Type 2 Diabetes: The DASH4D Randomized Clinical Trial.
Pilla SJ, Yeh HC, Mitchell CM, Miller ER, et al · · 2025 · cited 5× · PMID 40489102 · DOI 10.1001/jamainternmed.2025.1580
DASH4D diet for glycemic control and glucose variability in type 2 diabetes: a randomized crossover trial.
Fang M, Wang D, Rebholz CM, Echouffo-Tcheugui JB, et al · · 2025 · cited 1× · PMID 40764427 · DOI 10.1038/s41591-025-03823-3
Design of the Continuous Glucose Monitoring (CGM) Study in the Dietary Approaches to Stop Hypertension for Diabetes Trial (DASH4D-CGM).
Wang D, Mu SZ, Tang O, Echouffo-Tcheugui JB, et al · · 2025 · cited 1× · PMID 39952551 · DOI 10.1016/j.cct.2025.107845
Fast Bayesian Functional Principal Components Analysis.
Sartini J, Zhou X, Selvin E, Zeger S, et al · · 2026 · PMID 41948477 · DOI 10.1080/10618600.2025.2592768

Verify or expand the search:

Other recruiting trials for Diabetes Mellitus, Type 2

Currently open trials in the same condition.

NCT07415954 — A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 · Phase 2 · recruiting
NCT07532863 — A Real-world Study to Investigate Cardiovascular Risk Profile Among Newly Diagnosed Type 2 Diabetes Mellitus (T2DM) Part · recruiting
NCT07336329 — Continuous Glucose Monitoring in Non-Insulin Treated Type 2 Diabetes: Continuous vs. Periodic Use · NA · recruiting
NCT07242469 — A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006) · Phase 1 · recruiting
NCT07444203 — Transformative Research in Diabetic Nephropathy 2.0 · recruiting

Other Johns Hopkins University trials

Trials by the same sponsor.

NCT06236542 — Tracheostomy Robotics and Cutting-edge Health Education for Airway Safety · NA · not yet recruiting
NCT07532252 — Daridorexant for Alcohol Use Disorder · Phase 2 · not yet recruiting
NCT06687655 — Impact of Exogenous Ketones on Sleep Apnea · Phase 1, PHASE2 · not yet recruiting
NCT07079111 — 3D Printed Occlusal Splints for Intraoperative Use · NA · not yet recruiting
NCT02998502 — The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04286555 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
Last refreshed: 20 November 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04286555.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing