Who is sponsoring NCT04286490?

NCT04286490 is sponsored by University Hospital, Grenoble.

What drugs are being tested in NCT04286490?

Interventions in NCT04286490: Prone position.

What condition does NCT04286490 study?

NCT04286490 studies Acute Respiratory Distress Syndrome, Acute Kidney Injury, Prone Position, Intra-Abdominal Hypertension.

Is NCT04286490 still recruiting?

NCT04286490 is currently completed. Last updated 29 January 2025.

Last reviewed 2025-01-29 · How we verify

NCT04286490: PRO-KIDNEY

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Prone Position and Renal Resistive Index

Completed NA Last updated 29 January 2025

What this trial tests

NA trial testing Prone position in Acute Respiratory Distress Syndrome in 20 participants. Completed in 30 June 2022.

Timeline

30 June 2020

Primary endpoint
30 June 2022

30 June 2022

Quick facts

Lead sponsor	University Hospital, Grenoble
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Enrollment	20
Start date	30 June 2020
Primary completion	30 June 2022
Estimated completion	30 June 2022
Sites	1 location across France

Drugs / interventions tested

Prone position

Conditions studied

Acute Respiratory Distress Syndrome — all drugs for Acute Respiratory Distress Syndrome →
Acute Kidney Injury — all drugs for Acute Kidney Injury →
Prone Position — all drugs for Prone Position →
Intra-Abdominal Hypertension — all drugs for Intra-Abdominal Hypertension →

Sponsor

University Hospital, Grenoble

Who can join

18 and older, any sex, with Acute Respiratory Distress Syndrome or Acute Kidney Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients suffering from Acute Respiratory Distress Syndrome (ARDS) with a prone position (PP) indication will benefit from measurements of renal resistive index, intra-abdominal pressure (IAP), urinary oxygen tension (uPO2) and ventilatory mechanics in supine position (baseline IAP), after 2 hours in PP at the current IAP value, thirty minutes after patients' abdomen suspension in order to resume baseline IAP and after patients' are turned back to supine position.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Impact of Dexamethasone and Inhaled Nitric Oxide on Severe Acute Kidney Injury in Critically Ill Patients with COVID-19.
Bobot M, Tonon D, Peres N, Guervilly C, et al · · 2022 · cited 12× · PMID 36294451 · DOI 10.3390/jcm11206130
Impact of Dexamethasone and Inhaled Nitric Oxide on Severe Acute Kidney Injury in Critically Ill Patients with COVID-19
Bobot M, Tonon D, Peres N, Guervilly C, et al · · 2022 · DOI 10.21203/rs.3.rs-1374844/v1

Verify or expand the search:

Other trials of Prone position

Trials testing the same drug.

NCT07083973 — Prone Position Assessed by 3D EIT · recruiting
NCT07251777 — Prone vs Supine Position in Potential Organ Donors: Multicenter Clinical Trial · NA · completed
NCT04596202 — The Effect of Position on Gastric Residual Volume and Comfort Level in Newborns · NA · completed
NCT06076109 — Early Awake Alterning Prone Positioning Combined With Non-invasive Oxygen Therapy in Patients With COVID-19. · NA · terminated
NCT04904731 — Effects of Body Position on Diaphragmatic Activity in Patients Requiring Noninvasive Ventilation for Acute Respiratory F · completed

Other recruiting trials for Acute Respiratory Distress Syndrome

Currently open trials in the same condition.

NCT07284888 — Practices of Prone Positioning Ventilation in Patients With Moderate-to-Severe ARDS in Intensive Care Units: A Registry- · recruiting
NCT07289711 — Validation and Precision Treatment of Inflammatory Subphenotypes in Acute Respiratory Distress Syndrome: A Multicenter C · recruiting
NCT07326215 — A Study of the Efficacy and Safety of Extracorporeal Carbon Dioxide Removal Using PrismaLung+ · NA · recruiting
NCT06919484 — The Physiological Effect of RCexp on Ventilation/Perfusion Distribution · recruiting
NCT07126964 — Extended Prone Positioning for Intubated ARDS · NA · recruiting

Other University Hospital, Grenoble trials

Trials by the same sponsor.

NCT07479225 — Circulating Cell-Free DNA for Brain Abscess Diagnosis: A Pilot Study · NA · not yet recruiting
NCT07477613 — Implantable Brain-Computer Interface for Upper-Limb Recovery After Stroke · NA · not yet recruiting
NCT07379372 — Bladder Overactivity and Post-Botulinum Toxin Telemonitoring · NA · not yet recruiting
NCT07166991 — Anesthesia sTrategy foR Organ Procurement In braiN dEath · Phase 3 · recruiting
NCT07367880 — The Monument Test : A New Tool for Assessing the Ability to Name and Identify Unique Entities. (TeDIMO) · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04286490 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital, Grenoble
Last refreshed: 29 January 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04286490.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing