Last reviewed · How we verify
NCT04904731: DiaCOVIDProne
Effects of Body Position on Diaphragmatic Activity in Patients Requiring Noninvasive Ventilation for Acute Respiratory Failure COVID-19 Related
trial testing Prone position in Noninvasive Ventlation in 24 participants. Completed in 24 May 2021.
12 May 2021
Quick facts
| Lead sponsor | Azienda Ospedaliera di Perugia |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 24 |
| Start date | 19 February 2021 |
| Primary completion | 12 May 2021 |
| Estimated completion | 24 May 2021 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Prone position
Conditions studied
- Noninvasive Ventlation — all drugs for Noninvasive Ventlation →
- COVID-19 Respiratory Infection — all drugs for COVID-19 Respiratory Infection →
- Diaphragm Injury — all drugs for Diaphragm Injury →
Sponsor
Azienda Ospedaliera di Perugia — full company profile →
Who can join
18 and older, any sex, with Noninvasive Ventlation or COVID-19 Respiratory Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The present investigation aims to assess the diaphragmatic thickening fraction, reflecting the diaphragmatic activity, during supine (baseline) and at 1 hour following prone position in patients assisted through non invasive ventilation due to hypoxemic acute respiratory failure related to COVID-19. Also, the impact of lung aeration and comfort were ascertained in the same setting
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04904731
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Prone position
Trials testing the same drug.
- NCT07083973 — Prone Position Assessed by 3D EIT · recruiting
- NCT07251777 — Prone vs Supine Position in Potential Organ Donors: Multicenter Clinical Trial · NA · completed
- NCT04596202 — The Effect of Position on Gastric Residual Volume and Comfort Level in Newborns · NA · completed
- NCT06076109 — Early Awake Alterning Prone Positioning Combined With Non-invasive Oxygen Therapy in Patients With COVID-19. · NA · terminated
- NCT04543760 — Effect of Prone Positioning Combined With High Flow Oxygen Therapy on Oxygenation During Acute Respiratory Failure Due t · NA · completed
Other Azienda Ospedaliera di Perugia trials
Trials by the same sponsor.
- NCT07050940 — Anti PD-1 Plus Postbiotic Versus Anti PD-1 Alone in Locally Advanced or Metastatic, Treatment naïve, Cutaneous Melanoma · NA · recruiting
- NCT06458478 — Effects of the Application of a Hyper-oxygenated Gel After Oral Surgery · NA · recruiting
- NCT05702554 — Recruitment-to-inflation Ratio to Set Positive End-expiratory Pressure for Laparoscopic/Robotic Surgery: a Multicenter S · unknown
- NCT07480187 — Toward Molecular Profiling of Parkinson's Disease in Easily Accessible Biological Matrices · NA · active not recruiting
- NCT05125744 — Effect of Positive End Expiratory Pressure on Diaphragmatic Fraction Assessed Through Ultrasound in Intubated Patient Un · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04904731 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Azienda Ospedaliera di Perugia
- Last refreshed: 27 May 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04904731.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing