NCT04277182 is a NA clinical trial of burn wound dressing in Burns, sponsored by Izmir Katip Celebi University.

Who is sponsoring NCT04277182?

NCT04277182 is sponsored by Izmir Katip Celebi University.

What drugs are being tested in NCT04277182?

Interventions in NCT04277182: burn wound dressing.

What condition does NCT04277182 study?

NCT04277182 studies Burns, Burn Wound.

Is NCT04277182 still recruiting?

NCT04277182 is currently completed. Last updated 3 August 2022.

Last reviewed 2022-08-03 · How we verify

NCT04277182

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Propolis Application on Burn Healing

Completed NA Last updated 3 August 2022

What this trial tests

NA trial testing burn wound dressing in Burns in 36 participants. Completed in 28 September 2020.

Timeline

1 September 2020

Primary endpoint
28 September 2020

28 September 2020

Quick facts

Lead sponsor	Izmir Katip Celebi University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	36
Start date	1 September 2020
Primary completion	28 September 2020
Estimated completion	28 September 2020
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

burn wound dressing — full drug profile →

Conditions studied

Burns — all drugs for Burns →
Burn Wound — all drugs for Burn Wound →

Sponsor

Izmir Katip Celebi University

Who can join

Adults 8 Weeks to 12 Weeks, any sex, with Burns or Burn Wound. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This experimental study will be carried out at Ege University Laboratory Animals Application and Research Center to identify the efficacy of 10% propolis and 15% propolis on wound healing in a second-degree superficial burn wound. In the study, 36 adult (8-12 week old) Wistar-Albino rats with a weight of 200-300 grams will be used in each group. Each group will include 6 rats. Stratified randomization will be used to randomize rats according to their gender and weight. After randomization, a burnt area will be created on the back of the rats and dressings will be made every day. Following the creation of the burn, biopsy samples will be taken on the 3rd, 7th, 14th and 21st days and at the light microscopic level; bulla, erythema, oedema, burn depth, inflammatory cell infiltration, necrosis, ulceration, angiogenesis, neovascularization, fibroblast proliferation, collagenization, epithelization, fibrosis, the number of hair follicles and damage to the skin attachments. In the immunohistochemical examination of biopsy samples, samples will be taken for the evaluation of superoxide dismutase, malondialdehyde, myeloperoxidase in the evaluation of the tumour necrosis factor-alpha, interleukin-1β and oxidative stress in the EBB period in order to evaluate the acute phase reactants. Fungal and gram staining will be done in order to determine the pathogen reproduction in biopsy samples taken on the 3rd and 7th day. Masson trichrome in order to detect fibrosis in biopsy samples taken on the 14th and 21st day; Hydroxyproline examination will be examined in order to evaluate collagen formation.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Burns

Currently open trials in the same condition.

NCT07259668 — Lipopolysaccharide Adsorption (Efferon LPS) in Patients With Thermal Burns · recruiting
NCT07248930 — Lipopolysaccharide Adsorption (Efferon LPS NEO) in Children With Thermal Burns · recruiting
NCT07313735 — The Effect of Cartoon Character-Printed Band Use During Burn Dressing on Fear, Stress, Pain, and Physiological Parameter · NA · recruiting
NCT07142824 — Comparison Between Burn Dressing Using Tilapia-Fish Skin Versus Regular Dressing · NA · recruiting
NCT07277166 — The Effect of Mobile Robot Assisted Gait Training on Gait Performance in Chronic Patients With Impaired Gait Function Af · NA · recruiting

Other Izmir Katip Celebi University trials

Trials by the same sponsor.

NCT07460479 — Pilot Study of an Extended CBT Group Intervention for Intolerance of Uncertainty · NA · recruiting
NCT07453277 — Blood-Based Molecular Clock Biomarkers Predict Acute Ischemic Stroke Onset: A Prospective Observational Study · active not recruiting
NCT07341646 — Effect of Cuff Pressure Assessment Methods on Postoperative Complications in Breast Surgery · NA · not yet recruiting
NCT07304661 — Comparison of PPV and LVOT VTI During Passive Leg Raising to Predict Fluid Responsiveness · not yet recruiting
NCT07304648 — Role of End-Tidal CO2 During Passive Leg Raising to Predict Fluid Responsiveness in ICU · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04277182 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Izmir Katip Celebi University
Last refreshed: 3 August 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04277182.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing