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NCT04272268: Hi-FLO
Feasibility and Safety of Using Nasal High Flow Oxygen Postoperatively to Reduce Respiratory Complications
trial testing Nasal High flow Oxygen in Cancer of the Esophagus. Withdrawn.
31 March 2020
Quick facts
| Lead sponsor | University Hospitals of North Midlands NHS Trust |
|---|---|
| Status | Withdrawn |
| Study type | OBSERVATIONAL |
| Start date | 1 October 2019 |
| Primary completion | 31 March 2020 |
| Estimated completion | 31 March 2020 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Nasal High flow Oxygen
Conditions studied
- Cancer of the Esophagus — all drugs for Cancer of the Esophagus →
Sponsor
University Hospitals of North Midlands NHS Trust
Who can join
18 and older, any sex, with Cancer of the Esophagus. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The use of nasal high flow in patients undergoing oesophagectomy is a novel technique that has not been previously studied. Nasal high flow will be delivered postoperatively to patients undergoing oesophagectomy in a tertiary cancer referral centre. This single-centre cohort study will evaluate the safety of using nasal high flow in oesophagectomy patients. Physiological parameters, adverse events and clinical outcome will be recorded in consecutive patients undergoing oesophagogastric surgery. This study will challenge the hypothesis that the use of nasal high-flow will lower the rates of breathing complications such as pneumonia thereby reducing the demands on intensive care, shortening hospital stay and improving patient quality of life. The results will inform the design of a larger multicentre clinical trial comparing nasal high flow to conventional methods by facilitating sample size calculation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04272268
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Related trials
Other recruiting trials for Cancer of the Esophagus
Currently open trials in the same condition.
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- NCT03482791 — Proton Beam Therapy in the Treatment of Esophageal Cancer · NA · active not recruiting
Other University Hospitals of North Midlands NHS Trust trials
Trials by the same sponsor.
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- NCT06050720 — Sleep Apnoea Breathing Record Exploratory Study (SABRES) · NA · active not recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04272268 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospitals of North Midlands NHS Trust
- Last refreshed: 15 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04272268.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing