NCT04267133

Video-based Detection of Atrial Fibrillation

Completed NA Results posted Last updated 27 January 2023

What this trial tests

NA trial testing Facial video of detection of cardiac disease in Atrial Fibrillation in 256 participants. Completed in 30 June 2021.

Timeline

24 May 2018

Primary endpoint
30 June 2021

30 June 2021

Quick facts

Lead sponsor	University of Rochester
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	256
Start date	24 May 2018
Primary completion	30 June 2021
Estimated completion	30 June 2021
Sites	1 location across United States

Drugs / interventions tested

• Facial video of detection of cardiac disease

Conditions studied

• Atrial Fibrillation — all drugs for Atrial Fibrillation →

Sponsor

University of Rochester

Who can join

18 and older, any sex, with Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Area Under the Receiver Operating Characteristic Curve (AUC) for the Detection of Atrial Fibrillation Primary · 2 weeks

The outcome measure is the AUC of the curve obtained from the ROC analysis. The curve is a combination of specificity and sensitivity of detecting atrial fibrillation. The range of the curve is 0.5-1.0 where 0.5 would be random detection of atrial fibrillation and 1.0 would be perfect performance.

Group	Value	95% CI
All Participants	0.74

Sponsor's own description

The project focuses on the evaluation of a novel, contactless monitoring technology to measure the blood pulsatile signal based on the video recording of an individual's face. The variability of the pulse rate is computed to identify the presence of atrial fibrillation (AF). We propose to enroll 315 patients with symptomatic AF, paroxysmal or persistent, who go through successful radiofrequency ablation or electrical cardioversion. A computer tablet will be used by the subjects at home during 14 days after their procedure to read emails, browse the internet and watch videos. Facial video recordings will be automatically acquired during these daily activities by the tablet device. The subject will be wearing an ECG patch during the follow-up period. The one-lead continuous ECG will be used as a reference to verify the presence of AF rhythm during facial video recordings. The primary aim of the study is to demonstrate the validity and robustness of the video-based technology to detect the presence of AF when facial videos are acquired by the patients at home.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Monitoring Pulse Rate in the Background Using Front Facing Cameras of Mobile Devices.
   Savur C, Dautov R, Bukum K, Xia X, et al · · 2023 · cited 1× · PMID 35939479 · DOI 10.1109/jbhi.2022.3197076
2. Identifying Demographic Factors Affecting the ECG Duration Collected Using a Single-Lead ECG Patch Device.
   Dzikowicz DJ, Aktas M, Mykins B, Xia X, et al · · 2025 · PMID 40320720 · DOI 10.1111/anec.70068