NCT04259398 is a NA clinical trial of Propofol in Cancer of Colon, sponsored by Seoul National University Hospital.

Who is sponsoring NCT04259398?

NCT04259398 is sponsored by Seoul National University Hospital.

What drugs are being tested in NCT04259398?

Interventions in NCT04259398: Propofol, Sevoflurane.

What condition does NCT04259398 study?

NCT04259398 studies Cancer of Colon, Anesthesia.

Is NCT04259398 still recruiting?

NCT04259398 is currently active, enrolled. Last updated 22 November 2023.

Last reviewed 2023-11-22 · How we verify

NCT04259398

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Anesthesia and Cancer Study: Colon Cancer

Active, enrolled NA Last updated 22 November 2023

What this trial tests

NA trial testing Propofol in Cancer of Colon in 797 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

18 February 2020

Primary endpoint
3 May 2028

3 May 2028

Quick facts

Lead sponsor	Seoul National University Hospital
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	797
Start date	18 February 2020
Primary completion	3 May 2028
Estimated completion	3 May 2028
Sites	2 locations across South Korea

Drugs / interventions tested

Propofol (Propofol) — full drug profile →
Sevoflurane — full drug profile →

Conditions studied

Cancer of Colon — all drugs for Cancer of Colon →
Anesthesia — all drugs for Anesthesia →

Sponsor

Seoul National University Hospital

Who can join

Adults 19 to 80, any sex, with Cancer of Colon or Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study investigates the influence of type of anesthesia on survival and recurrence rate in patients receiving colon cancer surgery. The participants will be allocated to either the TIVA group and the inhalation group.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Anaesthetic Techniques and Strategies: Do They Influence Oncological Outcomes?
Murphy L, Shaker J, Buggy DJ. · · 2023 · cited 3× · PMID 37366886 · DOI 10.3390/curroncol30060403
Propofol-based intravenous anesthesia is associated with improved survival outcomes after major cancer surgery: a nationwide cohort study in South Korea.
Oh TK, Jo H, Jo H, Song IA. · · 2023 · cited 2× · PMID 36824045 · DOI 10.4097/kja.22747

Verify or expand the search:

Other trials of Propofol

Trials testing the same drug.

NCT07251101 — Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery · NA · not yet recruiting
NCT07294092 — Ketamine and Propofol NeuroImaging · EARLY_PHASE1 · recruiting
NCT07269808 — Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration · Phase 3 · recruiting
NCT07460050 — Comparison of Two Sedative Agents in Terms of Controlled Hypotension · NA · not yet recruiting
NCT07347496 — A Randomized, Controlled Clinical Trial Comparing Remimazolam Besylate Combined With Alfentanil Versus Propofol Combined · Phase 4 · not yet recruiting

Other recruiting trials for Cancer of Colon

Currently open trials in the same condition.

NCT05163028 — A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations · Phase 1 · active not recruiting
NCT05179824 — Tempus Priority Study: A Pan-tumor Observational Study · active not recruiting

Other Seoul National University Hospital trials

Trials by the same sponsor.

NCT07262944 — EOI Block in Otoplasty With Rib Cartilage Graft · NA · recruiting
NCT07464210 — Nemtabrutinib, Bortezomib, and Rituximab for WM · Phase 2 · not yet recruiting
NCT07550803 — Effect of Intraoperative Dexamethasone on Early Postoperative Sleep Quality in Patients Undergoing Nasal Surgery · NA · not yet recruiting
NCT07522138 — Home-based Self-exercise in Patients With Parkinson's Disease: A Feasibility Study · NA · not yet recruiting
NCT07476651 — Scout Dose of Resin Microspheres · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04259398 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Seoul National University Hospital
Last refreshed: 22 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04259398.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing