Who is sponsoring NCT04234412?

NCT04234412 is sponsored by Uijeongbu St. Mary Hospital.

What drugs are being tested in NCT04234412?

Interventions in NCT04234412: umbilical cord blood stem cell implantation for osteoarthritis treatment.

What condition does NCT04234412 study?

NCT04234412 studies Osteoarthritis, Knee.

Is NCT04234412 still recruiting?

NCT04234412 is currently status unknown. Last updated 21 January 2020.

Last reviewed 2020-01-21 · How we verify

NCT04234412

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Treatment of Osteoarthritic Knee With High Tibial Osteotomy and Implantation of Allogenic Human Umbilical Cord Blood-derived Stem Cells.

Status unknown NA Last updated 21 January 2020

What this trial tests

NA trial testing umbilical cord blood stem cell implantation for osteoarthritis treatment in Osteoarthritis, Knee in 10 participants. Status unknown.

Timeline

1 February 2020

Primary endpoint
30 November 2022

30 November 2022

Quick facts

Lead sponsor	Uijeongbu St. Mary Hospital
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	10
Start date	1 February 2020
Primary completion	30 November 2022
Estimated completion	30 November 2022

Drugs / interventions tested

umbilical cord blood stem cell implantation for osteoarthritis treatment

Conditions studied

Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →

Sponsor

Uijeongbu St. Mary Hospital

Who can join

Adults 30 to 65, any sex, with Osteoarthritis, Knee. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to evaluate the clinical results after implantation of human umbilical cord blood-derived mesenchymal stem cells(hUCB-MSCs) and High tibia osteotomy in patients with medial compartment osteoarthritis(MCOA) as well as varus deformity of the knee joint. This study will prospectively evaluate 10 knees after hUCB-MSCs implantation and High Tibial Osteotomy(HTO) in the medial compartment osteoarthritis and varus deformity of the knee joint. Clinical outcomes will be evaluated using the International Knee Documentation committee(IKDC), Visual analogue scale(VAS), Western Ontario and McMaster Universities Arthritis Index(WOMAC), and patients satisfaction with the surgery.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Allogenic Perinatal Tissue for Musculoskeletal Regenerative Medicine Applications: A Systematic Review.
Aratikatla A, Maffulli N, Rodriguez HC, Gupta M, et al · · 2022 · cited 14× · PMID 36551929 · DOI 10.3390/biomedicines10123173
Wharton's jelly mesenchymal stem cells: Future regenerative medicine for clinical applications in mitigation of radiation injury.
Sharma P, Maurya DK. · · 2024 · cited 12× · PMID 39086560 · DOI 10.4252/wjsc.v16.i7.742
Treatment of osteoarthritic knee with high tibial osteotomy and allogeneic human umbilical cord blood-derived mesenchymal stem cells combined with hyaluronate hydrogel composite.
Bae BS, Jung JW, Jo GO, Kim SA, et al · · 2025 · cited 1× · PMID 40296133 · DOI 10.1186/s13287-025-04356-9

Verify or expand the search:

Other recruiting trials for Osteoarthritis, Knee

Currently open trials in the same condition.

NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
NCT06488144 — Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans · Phase 3 · recruiting
NCT07386561 — Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty · NA · active not recruiting
NCT07514598 — Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA) · NA · active not recruiting
NCT07058623 — Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement · NA · recruiting

Other Uijeongbu St. Mary Hospital trials

Trials by the same sponsor.

NCT07528404 — High-Flow Nasal Cannula After Major Abdominal Surgery to Prevent Postoperative Pulmonary Complications · NA · not yet recruiting
NCT03615300 — Predicting Long-term Outcomes After Cardiac Arrest by Using Serum NGAL · terminated
NCT03175965 — Prognostic Value of P30 After Cardiac Arrest · completed
NCT03236610 — Tenofovir Monotherapy in Patients With Chronic Hepatitis B Patients Who Had Achieved Complete Viral Suppression on Entec · Phase 3 · unknown
NCT03236584 — Tenofovir Monotherapy in Patients With Chronic Hepatitis B Patients Who Had Achieved Complete Viral Suppression on Lamiv · Phase 3 · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04234412 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Uijeongbu St. Mary Hospital
Last refreshed: 21 January 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04234412.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing