Last reviewed · How we verify
NCT04232072
Ibuprofen and Erector Spinae Plane Block After Laparoscopic Sleeve Gastrectomy
NA trial testing Group ESPB in Obesity. Withdrawn.
30 November 2020
Quick facts
| Lead sponsor | Medipol University |
|---|---|
| Phase | NA |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Start date | 11 February 2020 |
| Primary completion | 30 November 2020 |
| Estimated completion | 30 November 2020 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Group ESPB
- Group Ibuprofen
Conditions studied
- Obesity — all drugs for Obesity →
Sponsor
Medipol University
Who can join
Adults 18 to 65, any sex, with Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Laparoscopic sleeve gastrectomy (LSG) is defined as the first-step bariatric surgery for patients in the high surgical risk group. It has been shown that the laparoscopic approach has lower complication rates, shorter hospital stays, and earlier mobilization compared to open surgery. However, postoperative pain management is very important because it might cause major morbidity, especially pulmonary complications in the early postoperative period. The intravenous (IV) form of ibuprofen has been used in the pain treatment since 2009. It has been shown to be effective, safe and with less adverse effects in the treatment of postoperative pain. It has been reported that ibuprofen provides effective postoperative pain management after LSG surgery. The ultrasound (US) guided erector spina plane block (ESPB) is a novel interfacial plan block defined by Forero et al. ESPB provides thoracic analgesia at T5 level, abdominal analgesia at T7-9 level. In the literature, it has been reported that ESPB provides effective analgesia after LSG surgery. The aim of this study is to compare US-guided ESPB and IV ibuprofen for postoperative analgesia management after LSG surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Single-dose intravenous ibuprofen for acute postoperative pain in adults.
Ferguson MC, Schumann R, Gallagher S, McNicol ED. · · 2021 · cited 10× · PMID 34499349 · DOI 10.1002/14651858.cd013264.pub2
Verify or expand the search:
- PubMed search for NCT04232072
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Group ESPB
Trials testing the same drug.
- NCT05822492 — Anterior Quadratus Lumborum Block Versus Erector Spina Plane Block in Percutaneous Nephrolithotomy Surgery · completed
Other recruiting trials for Obesity
Currently open trials in the same condition.
- NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
- NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
- NCT07272837 — Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass · recruiting
- NCT07481630 — A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoart · Phase 3 · recruiting
- NCT07527195 — Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscl · Phase 1 · recruiting
Other Medipol University trials
Trials by the same sponsor.
- NCT07277803 — Device-Based vs Manual Sensory Training in Low Back Pain · NA · not yet recruiting
- NCT07214636 — Development and Investigation of the ApneaTheraPlay · NA · not yet recruiting
- NCT07534475 — Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT · NA · not yet recruiting
- NCT07534488 — Sacral Erector Spinae Plane Block in Pilonidal Sinus Surgery · NA · not yet recruiting
- NCT07525648 — Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04232072 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medipol University
- Last refreshed: 30 December 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04232072.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing