NCT04228029 is a Phase 4 clinical trial of Carboxytherapy in Alopecia Areata, sponsored by Kasr El Aini Hospital.

Who is sponsoring NCT04228029?

NCT04228029 is sponsored by Kasr El Aini Hospital.

What drugs are being tested in NCT04228029?

Interventions in NCT04228029: Carboxytherapy, Intralesional Steroid Injection.

What condition does NCT04228029 study?

NCT04228029 studies Alopecia Areata.

Is NCT04228029 still recruiting?

NCT04228029 is currently status unknown. Last updated 14 January 2020.

Last reviewed 2020-01-14 · How we verify

NCT04228029

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparative Study for Treatment of Alopecia Areata Using Carboxytherapy and Intralesional Steroids

Status unknown Phase 4 Last updated 14 January 2020

What this trial tests

Phase 4 trial testing Carboxytherapy in Alopecia Areata in 30 participants. Status unknown.

Timeline

20 August 2019

Primary endpoint
20 February 2020

20 April 2020

Quick facts

Lead sponsor	Kasr El Aini Hospital
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	sequential
Masking	double
Primary purpose	treatment
Enrollment	30
Start date	20 August 2019
Primary completion	20 February 2020
Estimated completion	20 April 2020
Sites	1 location across Egypt

Drugs / interventions tested

Carboxytherapy — full drug profile →
Intralesional Steroid Injection — full drug profile →

Conditions studied

Alopecia Areata — all drugs for Alopecia Areata →

Sponsor

Kasr El Aini Hospital

Who can join

Adults 18 to 50, any sex, with Alopecia Areata. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients with three lesions of alopecia areata are randomly recruited in this study. Each lesion is randomized in to receiving either carboxytherapy in one lesion, intralesional steroids in another lesion and combination of both in the third lesion. Treatment period is 3 months followed by a follow-up period of 2 months.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Comparative study for treatment of alopecia areata using carboxy therapy, intralesional corticosteroids, and a combination of both.
Metwally D, Abdel-Fattah R, Hilal RF. · · 2022 · cited 7× · PMID 33742252 · DOI 10.1007/s00403-021-02201-6

Verify or expand the search:

Other trials of Carboxytherapy

Trials testing the same drug.

NCT06791577 — Bridging the Healing Gap: A Single-Blind Clinical Trial Assessing the Efficacy of Carboxy-gel in Reducing Bruising and P · Phase 4 · recruiting
NCT05695807 — Carboxytherapy in the Treatment of Atrophic Scars · NA · unknown

Other recruiting trials for Alopecia Areata

Currently open trials in the same condition.

NCT07242638 — Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down Syndrome · Phase 2 · recruiting
NCT07311564 — A Study of LAD603 in Adults With Alopecia Areata · Phase 2 · recruiting
NCT07250997 — PALLAS Laser for Skin Diseases · NA · recruiting
NCT07205159 — A Study to Evaluate the Safety and Efficacy of FB102 in Patients With Severe to Very Severe Alopecia Areata. · Phase 1 · recruiting
NCT06747611 — Evaluation of Microbiota Transplant Therapy in Patients With Alopecia Areata · Phase 2 · recruiting

Other Kasr El Aini Hospital trials

Trials by the same sponsor.

NCT07438652 — Effect of Mediterranean vs Paleolithic Diet on RA Activity, Sarcopenia and QOL: 12-Week RCT · NA · recruiting
NCT07488039 — Labroplasty in Cases of Anterior Shoulder Instability With Subcritical Glenoid Bone Loss · NA · recruiting
NCT07274280 — Comparative Evaluation of Ambu AuraGain, LarySeal Pro and I-gel in Pediatric Airway Management for Day-Case Surgery Unde · NA · not yet recruiting
NCT07348146 — Hand-Sewn vs. Stapled Anastomosis in SADI-S: Early Postoperative Complications. · NA · enrolling by invitation
NCT07077265 — Comparing Two Different Norepinephrine Infusion Rates for Prophylaxis Against Spinal-induced Hypotension in Elderly · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04228029 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Kasr El Aini Hospital
Last refreshed: 14 January 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04228029.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing