NCT04227535 (TRANSLATE2) is a clinical trial in Rheumatoid Arthritis, sponsored by Assistance Publique - Hôpitaux de Paris.

Who is sponsoring NCT04227535?

NCT04227535 is sponsored by Assistance Publique - Hôpitaux de Paris.

What condition does NCT04227535 study?

NCT04227535 studies Rheumatoid Arthritis, Interstitial Lung Disease.

Is NCT04227535 still recruiting?

NCT04227535 is currently active, enrolled. Last updated 28 April 2023.

Last reviewed 2023-04-28 · How we verify

NCT04227535: TRANSLATE2

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Deciphering Rheumatoid Arthritis-associated Interstitial Lung Disease Pathogenesis 2

Active, enrolled Last updated 28 April 2023

What this trial tests

trial in Rheumatoid Arthritis in 509 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

3 February 2020

Primary endpoint
1 October 2027

1 October 2027

Quick facts

Lead sponsor	Assistance Publique - Hôpitaux de Paris
Status	Active, enrolled
Study type	OBSERVATIONAL
Enrollment	509
Start date	3 February 2020
Primary completion	1 October 2027
Estimated completion	1 October 2027
Sites	1 location across France

Conditions studied

Rheumatoid Arthritis — all drugs for Rheumatoid Arthritis →
Interstitial Lung Disease — all drugs for Interstitial Lung Disease →

Sponsor

Assistance Publique - Hôpitaux de Paris — full company profile →

Who can join

18 and older, any sex, with Rheumatoid Arthritis or Interstitial Lung Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The overall goal of this study is to identify risk and prognosis factors of Interstitial Lung Disease (ILD) in patients with rheumatoid arthritis (RA).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

A Risk Score to Detect Subclinical Rheumatoid Arthritis-Associated Interstitial Lung Disease.
Juge PA, Granger B, Debray MP, Ebstein E, et al · · 2022 · cited 74× · PMID 35583934 · DOI 10.1002/art.42162
Baseline characteristics of the TRANSLATE2 cohort: A prospective study on rheumatoid arthritis-associated interstitial lung disease.
Juge PA, Debray MP, Pensec VD, Richez C, et al · · 2026 · PMID 41110685 · DOI 10.1016/j.jbspin.2025.105991

Verify or expand the search:

Other recruiting trials for Rheumatoid Arthritis

Currently open trials in the same condition.

NCT07433335 — A Study to Assess the Safety and Tolerability of SR-878 in Patients With Rheumatoid Arthritis · Phase 1 · recruiting
NCT07491016 — Efficacy and Safety of Telitacicept Combined With Baricitinib for Refractory Rheumatoid Arthritis · recruiting
NCT07171983 — A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986454 in Participants With Rheumatoid Arthritis · Phase 1 · recruiting
NCT07246096 — Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Rel · EARLY_PHASE1 · recruiting
NCT07363590 — A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004) · Phase 1 · recruiting

Other Assistance Publique - Hôpitaux de Paris trials

Trials by the same sponsor.

NCT07443436 — Immunomodulatory Treatment of Interstitial Lung Disease Associated With Surfactant Related Gene Variants · Phase 2 · not yet recruiting
NCT07499492 — Red Blood Cell Transfusion to Optimize Extubation · NA · not yet recruiting
NCT07379918 — Real-life Evaluation of Endopredict® in Early HR+/HER2- Breast Cancer · recruiting
NCT07473869 — Smartphone Application for Automated Measurement of Capillary Refill Time (CRT) · not yet recruiting
NCT07505394 — Efficacy of a Prediction Model-based Algorithm to PREVENT Drug-induced Impulse Control Disorders in Parkinson's Disease · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04227535 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Assistance Publique - Hôpitaux de Paris
Last refreshed: 28 April 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04227535.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing