Who is sponsoring NCT04215965?

NCT04215965 is sponsored by Assistance Publique Hopitaux De Marseille.

What drugs are being tested in NCT04215965?

Interventions in NCT04215965: Biphozyl (dialysate and replacement), Prismocal B22 (dialysate) + phoxilium (replacement).

What condition does NCT04215965 study?

NCT04215965 studies Critical Care.

Is NCT04215965 still recruiting?

NCT04215965 is currently status unknown. Last updated 2 January 2020.

Last reviewed 2020-01-02 · How we verify

NCT04215965: Phosphorus

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy and Safety of a Citrate-based Anticoagulation With Calcium-free Phosphate-containing Fluid in Renal Replacement Therapy

Status unknown Phase 4 Last updated 2 January 2020

What this trial tests

Phase 4 trial testing Biphozyl (dialysate and replacement) in Critical Care in 100 participants. Status unknown.

Timeline

2 May 2020

Primary endpoint
1 August 2021

1 August 2022

Quick facts

Lead sponsor	Assistance Publique Hopitaux De Marseille
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	100
Start date	2 May 2020
Primary completion	1 August 2021
Estimated completion	1 August 2022

Drugs / interventions tested

Biphozyl (dialysate and replacement) — full drug profile →
Prismocal B22 (dialysate) + phoxilium (replacement) — full drug profile →

Conditions studied

Critical Care — all drugs for Critical Care →

Sponsor

Assistance Publique Hopitaux De Marseille — full company profile →

Who can join

18 and older, any sex, with Critical Care. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In the present prospective multicenter RCT we will evaluate the effects on efficacy, acid-base status and serum phosphate levels of a new RCA protocol for Continuous Venovenous Hemodiafiltration (CVVHDF) using an 18 mmol/l citrate solution in combination with a calcium-free phosphate-containing solution, acting as dialysate and replacement fluid. The new protocol will be introduced with the following targets: a) to refine buffers balance of a previously adopted RCA protocol for Continuous Venovenous Hemofiltration (CVVH), based on a 18 mmol/l citrate solution (Regiocit) combined with calcium and phosphate-free dialysate fluid (PrismOcal B22) and a conventional phosphate-containing replacement fluid (Phoxilium) to prevent CRRT-related phosphate depletion

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

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Other Assistance Publique Hopitaux De Marseille trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04215965 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Assistance Publique Hopitaux De Marseille
Last refreshed: 2 January 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04215965.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing