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NCT04205318
FTO Gene Variants and Diet in Obesity
trial in Obesity in 400 participants. Completed in 31 December 2018.
1 February 2018
Quick facts
| Lead sponsor | Hacettepe University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 400 |
| Start date | 1 March 2017 |
| Primary completion | 1 February 2018 |
| Estimated completion | 31 December 2018 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Obesity — all drugs for Obesity →
- Diet Habit — all drugs for Diet Habit →
- Genetic Predisposition — all drugs for Genetic Predisposition →
Sponsor
Hacettepe University
Who can join
Adults 24 to 50, any sex, with Obesity or Diet Habit. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Studies have shown that the effect of fat mass and obesity-associated (FTO) gene on obesity is modulated by lifestyle factors. Hence, we aimed to determine whether two single nucleotide polymorphisms (SNPs) in the FTO gene are associated with obesity and to assess whether these associations were modified by lifestyle factors. The study included 200 obese and 200 non-obese individuals from Turkey. Our study suggests that the effect of the SNPs on obesity traits is likely to be influenced by lifestyle factors in this Turkish population.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
RNA modifications in cellular metabolism: implications for metabolism-targeted therapy and immunotherapy.
Liu WW, Zheng SQ, Li T, Fei YF, et al · · 2024 · cited 112× · PMID 38531882 · DOI 10.1038/s41392-024-01777-5 -
m5C RNA methylation in cancer: from biological mechanism to clinical perspectives.
Yuan F, Xia Y, Huang Z, Gao H, et al · · 2025 · cited 1× · PMID 40544318 · DOI 10.1186/s40001-025-02812-z
Verify or expand the search:
- PubMed search for NCT04205318
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04205318 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hacettepe University
- Last refreshed: 19 December 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04205318.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing