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NCT04196933
Analysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma
NA trial testing Temporal Binding Adaptation - PSS training in Migraine. Withdrawn.
31 December 2025
Quick facts
| Lead sponsor | Massachusetts Eye and Ear Infirmary |
|---|---|
| Phase | NA |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | basic science |
| Start date | 5 September 2019 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Temporal Binding Adaptation - PSS training
- Temporal Binding Adaptation - PSS adaptation with VI stimulation
- Chronic Motion-modulated Stimulation
Conditions studied
- Migraine — all drugs for Migraine →
- Vestibular Migraine — all drugs for Vestibular Migraine →
- Vestibular Schwannoma — all drugs for Vestibular Schwannoma →
- Motion Sickness — all drugs for Motion Sickness →
Sponsor
Massachusetts Eye and Ear Infirmary — full company profile →
Who can join
Adults 8 to 80, any sex, with Migraine or Vestibular Migraine. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Multiple sensory cues are typically generated by discrete events, and while they do not reach the cerebrum simultaneously, the brain can bind them temporally if they are interpreted as corresponding to a single event. The temporal binding of vestibular and non-vestibular sensory cues is poorly understood and has not been studied in detail, despite the fact that the vestibular system operates in an inherently multimodal environment. In this study, the researchers are investigating the physiology and pathophysiology of vestibular temporal binding by studying normal subjects, patients with peripheral and central vestibular dysfunction, and patients with vestibular and cochlear signals provided by prosthetic implants in the inner ear.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04196933
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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- NCT07336056 — Nerivio Efficacy Under High-Frequency Use · Phase 4 · active not recruiting
- NCT07385755 — Desvenlafaxine for Preventive Treatment of Frequent Migraines · NA · active not recruiting
Other Massachusetts Eye and Ear Infirmary trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04196933 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Massachusetts Eye and Ear Infirmary
- Last refreshed: 16 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04196933.
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