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NCT04193020: ACID LTR

Acute and Chronic Inflammatory Disease, Lifestyle and Treatment Response

Status unknown Last updated 20 April 2021
What this trial tests

trial testing Surveillance card in Uveitis in 300 participants. Status unknown.

Timeline
1 January 2020
Primary endpoint
1 January 2025
1 January 2026

Quick facts

Lead sponsorWroclaw Medical University
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment300
Start date1 January 2020
Primary completion1 January 2025
Estimated completion1 January 2026
Sites1 location across Poland

Drugs / interventions tested

Conditions studied

Sponsor

Wroclaw Medical University

Who can join

Eligibility, any sex, with Uveitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute and chronic inflammatory eye diseases are difficult to diagnose and maintain quiescent with therapy. Proposed study is aimed to find on the one hand, novel factors for recurrence of the disease or remission of inflammation and evaluation of the impact of lifestyle and known factors on the other. Each patient is treated in accordance to the best of medical knowledge and guidelines for each disease. This prospective cohort study will enroll uveitic patients to the steroid only group (SG), combined (steroid and adjuvant drug) group (CG) or bilogic therapy group (BTG). At baseline, patient data are recorded using patient-reported outcome measures and clinical assessments (ophthalomology) on disease activity (clinical scales), quality of life, and lifestyle together with registry data on comorbidity and medication. During follow-up evaluation of a successful treatment outcome response will be based on clinical scales and most frequently used primary endpoints; the major outcome of the analyses will be to detect differences in treatment outcome between patients in different treatment group.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Imbalance in PB IL-17-Secreting and Regulatory Cells in Pars Planitis Is Associated with Dysregulation of IFN-<i>γ</i>-Secreting Cells, Especially in Patients with Clinical Complications.
    Kosmaczewska A, Przeździecka-Dołyk J, Turno-Kręcicka A, Ciszak L, et al · · 2020 · cited 2× · PMID 32801998 · DOI 10.1155/2020/9175083

Verify or expand the search:

Other recruiting trials for Uveitis

Currently open trials in the same condition.

Other Wroclaw Medical University trials

Trials by the same sponsor.

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Data sources for this page

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