NCT04189198 is a Phase 1 clinical trial of Articaine in Upper Limb Surgery, sponsored by Ain Shams University.

Who is sponsoring NCT04189198?

NCT04189198 is sponsored by Ain Shams University.

What drugs are being tested in NCT04189198?

Interventions in NCT04189198: Articaine, Bupivacaine.

What condition does NCT04189198 study?

NCT04189198 studies Upper Limb Surgery, Hand Surgery.

Is NCT04189198 still recruiting?

NCT04189198 is currently completed. Last updated 28 April 2020.

Last reviewed 2020-04-28 · How we verify

NCT04189198

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Comparison of 4% Articaine Versus 0.5%Bupivacaine for Ambulatory Surgery Under Supraclavicular Block

Completed Phase 1 Last updated 28 April 2020

What this trial tests

Phase 1 trial testing Articaine in Upper Limb Surgery in 60 participants. Completed in 27 March 2020.

Timeline

30 December 2019

Primary endpoint
22 March 2020

27 March 2020

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	health services research
Enrollment	60
Start date	30 December 2019
Primary completion	22 March 2020
Estimated completion	27 March 2020
Sites	1 location across Egypt

Drugs / interventions tested

Articaine (ARTICAINE) — full drug profile →
Bupivacaine (BUPIVACAINE) — full drug profile →

Conditions studied

Upper Limb Surgery — all drugs for Upper Limb Surgery →
Hand Surgery — all drugs for Hand Surgery →

Sponsor

Ain Shams University

Who can join

Adults 18 to 75, any sex, with Upper Limb Surgery or Hand Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Effect of 2%Articaine versus 5%bupivacaine in pt undergoing short duration surgery in upper limb

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

A Randomized Controlled Trial: Comparison of 4% Articaine versus 0.5% Bupivacaine for Ambulatory Orthopedic Surgery under Supraclavicular Block.
Armanious SH, Abdelhameed GA. · · 2020 · PMID 33029135 · DOI 10.1155/2020/2194873

Verify or expand the search:

Other trials of Articaine

Trials testing the same drug.

NCT06423859 — Articaine Plus Dexmedetomidine in Supraclavicular Block · NA · recruiting
NCT05443009 — Self-Reported Pain in Children Submitted to Single Infiltration of Articaine During Primary Molar Extraction · Phase 4 · completed
NCT04171349 — Articaine vs Dexmedetomidine Supplemented Articaine · EARLY_PHASE1 · completed
NCT02726620 — Decision Support for Intraoperative Low Blood Pressure · NA · completed

Other recruiting trials for Upper Limb Surgery

Currently open trials in the same condition.

NCT07034300 — Lidocaine vs. Lidocaine With Dexmedetomidine for Intravenous Regional Anesthesia (IVRA) in Upper Limb Surgery · Phase 4 · recruiting
NCT06949488 — Efficacy of Different Medications as Adjuvants in Ultrasound-guided Supraclavicular Brachial Plexus Block in Forearm Sur · NA · active not recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04189198 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 28 April 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04189198.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing