NCT04171349 is a EARLY_PHASE1 clinical trial of Articaine in Renal Failure, sponsored by Ain Shams University.

Who is sponsoring NCT04171349?

NCT04171349 is sponsored by Ain Shams University.

What drugs are being tested in NCT04171349?

Interventions in NCT04171349: Articaine, Dexmedetomidine.

What condition does NCT04171349 study?

NCT04171349 studies Renal Failure.

Is NCT04171349 still recruiting?

NCT04171349 is currently completed. Last updated 20 November 2019.

Last reviewed 2019-11-20 · How we verify

NCT04171349

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Articaine vs Dexmedetomidine Supplemented Articaine

Completed EARLY_PHASE1 Last updated 20 November 2019

What this trial tests

EARLY_PHASE1 trial testing Articaine in Renal Failure in 50 participants. Completed in 1 November 2019.

Timeline

1 June 2019

Primary endpoint
1 October 2019

1 November 2019

Quick facts

Lead sponsor	Ain Shams University
Phase	EARLY_PHASE1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	50
Start date	1 June 2019
Primary completion	1 October 2019
Estimated completion	1 November 2019
Sites	1 location across Egypt

Drugs / interventions tested

Articaine (ARTICAINE) — full drug profile →
Dexmedetomidine (dexmedetomidine) — full drug profile →

Conditions studied

Renal Failure — all drugs for Renal Failure →

Sponsor

Ain Shams University

Who can join

Adults 25 to 75, any sex, with Renal Failure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study to test efficacy of adding dexmedetomidine to articaine on sensory, motor and duration of analgesia during hemodialysis fistula creation under ultrasound guided supraclavicular block

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Articaine and Dexmedetomidine - Supplemented Articaine for Arteriovenous Fistula Creation under Ultrasound-guided Supraclavicular Block.
Armanious SH, Abdelhameed GA. · · 2020 · PMID 33487824 · DOI 10.4103/aer.aer_147_19

Verify or expand the search:

Other trials of Articaine

Trials testing the same drug.

NCT06423859 — Articaine Plus Dexmedetomidine in Supraclavicular Block · NA · recruiting
NCT05443009 — Self-Reported Pain in Children Submitted to Single Infiltration of Articaine During Primary Molar Extraction · Phase 4 · completed
NCT04189198 — A Comparison of 4% Articaine Versus 0.5%Bupivacaine for Ambulatory Surgery Under Supraclavicular Block · Phase 1 · completed
NCT02726620 — Decision Support for Intraoperative Low Blood Pressure · NA · completed

Other recruiting trials for Renal Failure

Currently open trials in the same condition.

NCT07293936 — Post-Filter Hematocrit · NA · recruiting
NCT06814327 — Assessment of Organ Failure Risk Predictions in ICU · active not recruiting
NCT06203977 — Inflammation REduction to Prevent cArdiovascular Injury in Renal Disease (REPAIR) · Phase 1 · recruiting
NCT06142396 — Pilot Study Dara-CyBorD in Newly Diagnosed Multiple Myeloma Patients With Renal Failure · EARLY_PHASE1 · recruiting
NCT06620523 — Prevent Cardiac Surgery Associated AKI Trial · Phase 2 · recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04171349 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 20 November 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04171349.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing