NCT04187768 is a clinical trial in Non Small Cell Lung Cancer, sponsored by Indiana University.

Who is sponsoring NCT04187768?

NCT04187768 is sponsored by Indiana University.

What condition does NCT04187768 study?

NCT04187768 studies Non Small Cell Lung Cancer, Non Small Cell Lung Cancer Metastatic, Healthy.

Is NCT04187768 still recruiting?

NCT04187768 is currently completed. Last updated 20 July 2022.

Last reviewed 2022-07-20 · How we verify

NCT04187768

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Immunological Profile Changes In Patients With Advanced Non-Small Cell Lung Cancer

Completed Last updated 20 July 2022

What this trial tests

trial in Non Small Cell Lung Cancer in 29 participants. Completed in 13 June 2022.

Timeline

26 November 2019

Primary endpoint
13 June 2022

13 June 2022

Quick facts

Lead sponsor	Indiana University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	29
Start date	26 November 2019
Primary completion	13 June 2022
Estimated completion	13 June 2022
Sites	1 location across United States

Conditions studied

Non Small Cell Lung Cancer — all drugs for Non Small Cell Lung Cancer →
Non Small Cell Lung Cancer Metastatic — all drugs for Non Small Cell Lung Cancer Metastatic →
Healthy — all drugs for Healthy →

Sponsor

Indiana University

Who can join

18 and older, any sex, with Non Small Cell Lung Cancer or Non Small Cell Lung Cancer Metastatic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a blood collection study being conducted to better understand and describe the immunological blood profile changes in patients with advanced non small cell lung cancer undergoing treatment with checkpoint inhibitor therapy. Blood will be collected from healthy volunteers and patients with non small cell lung cancer

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Immune profiling in oncology: bridging the gap between technology and treatment.
Ravi N, Tye GJ, Dhaliwal SS, Musa MY, et al · · 2025 · cited 3× · PMID 40856894 · DOI 10.1007/s12032-025-03002-x

Verify or expand the search:

Other recruiting trials for Non Small Cell Lung Cancer

Currently open trials in the same condition.

NCT06951646 — ctDNA-MRD Guided Escalation of Ivonescimab and Docetaxel in Advanced NSCLC With Long-Term Responses to First-line Immuno · Phase 2 · recruiting
NCT07503808 — A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types · Phase 1 · recruiting
NCT07269782 — A Phase II Study to Evaluate the Efficacy and Safety of HLX43 + Serplulimab as Neoadjuvant Therapy in Subjects With NSCL · Phase 2 · recruiting
NCT07306624 — Nelmastobart in Combination With Docetaxel in Non Small Cell Lung Cancer · Phase 2 · recruiting
NCT07323732 — A Study of BIO 300 and Thoracic Radiation Therapy in People With Non-Small Cell Lung Cancer and Interstitial Lung Diseas · Phase 2 · recruiting

Other Indiana University trials

Trials by the same sponsor.

NCT07470086 — The Role of Environmental Temperatures in Respiratory Control · NA · not yet recruiting
NCT07470099 — The Role of Breathing Perception in Respiratory Control · NA · not yet recruiting
NCT07179952 — Efficacy and Safety of Slow Release Dehydroepiandrosterone (DHEA ) · Phase 2 · not yet recruiting
NCT07070804 — Maternal Biomarkers and Environmental Contributors to Autism Spectrum Disorders in Children of First-time Mothers · not yet recruiting
NCT07499583 — Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder · Phase 1, PHASE2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04187768 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Indiana University
Last refreshed: 20 July 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04187768.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing