Last reviewed · How we verify
NCT04180241: POEM
Development of Endoscopic Treatment for Achalasia
NA trial testing POEM in Achalasia in 55 participants. Participants enrolled and being followed up; not accepting new ones.
31 December 2026
Quick facts
| Lead sponsor | Karolinska Institutet |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 55 |
| Start date | 15 April 2019 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2027 |
| Sites | 2 locations across Sweden |
Drugs / interventions tested
- POEM
Conditions studied
- Achalasia — all drugs for Achalasia →
Sponsor
Karolinska Institutet
Who can join
Adults 18 to 70, any sex, with Achalasia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Per Oral Endoscopic Myotomy (POEM); comparison of two surgical techniques division all the esophageal muscle layers versus division the inner circular muscle layer of the esophagus only.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04180241
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of POEM
Trials testing the same drug.
- NCT07167355 — Comparison of Balloon Dilatation and Per Oral Endoscopic Myotomy in Children With Achalasia Cardia · NA · not yet recruiting
- NCT03587337 — Risk of Microbial Translocation in Patients Undergoing Per-Oral Endoscopic Myotomy (POEM) for Achalasia: Antibiotic Prop · completed
Other recruiting trials for Achalasia
Currently open trials in the same condition.
- NCT07496840 — Clinical Outcomes, Safety, and Effectiveness of Speedboat UltraSlim™ in Per-Oral Endoscopic Myotomy (POEM) · recruiting
- NCT07406945 — Safety and Efficacy of a Novel SpydrBlade Flexible Bipolar in POEM · NA · recruiting
- NCT06042127 — POEM-F for Achalasia International Study · NA · recruiting
- NCT05772260 — Autonomic Dysfunction and Hemodynamic Instability During Per-oral Endoscopic Myotomy · recruiting
- NCT07181070 — The Use of Indocyanine Green Fluorescence (ICG) During Laparoscopic Heller- Dor · recruiting
Other Karolinska Institutet trials
Trials by the same sponsor.
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- NCT07494266 — Safety of a Healthy Plant-based Diet With Higher Potassium Content, Compared to a Healthy Plant-based Diet With Limited · NA · not yet recruiting
- NCT07442032 — Cardiovascular Phenotypes in Sepsis · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04180241 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Karolinska Institutet
- Last refreshed: 8 May 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04180241.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing