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NCT04171583: mucostaph

Mucoid Staphylococcus Aureus in Cystic Fibrosis Airways

Completed Last updated 2 February 2023
What this trial tests

trial in Staphylococcus Aureus Pneumonia in 628 participants. Completed in 31 July 2022.

Timeline
1 March 2019
Primary endpoint
31 July 2022
31 July 2022

Quick facts

Lead sponsorUniversity Hospital Muenster
StatusCompleted
Study typeOBSERVATIONAL
Enrollment628
Start date1 March 2019
Primary completion31 July 2022
Estimated completion31 July 2022
Sites13 locations across Austria, Germany

Conditions studied

Sponsor

University Hospital Muenster

Who can join

Eligibility, any sex, with Staphylococcus Aureus Pneumonia or Lung Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Recently, the investigators described a new mucoid phenotype of Staphylococcus aureus cultured from the airways of cystic fibrosis (CF) patients.In this observational study, the investigators plan to determine the prevalence of mucoid S. aureus in respiratory specimens of CF patients and a possible impact of mucoid S. aureus on lung disease severity.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Mucoid <i>Staphylococcus aureus</i>: A Clinical Trial of Its Prevalence and Association with Lung Function in People with Cystic Fibrosis.
    Rumpf CH, Janssen T, Hait RJ, Romme K, et al · · 2025 · cited 2× · PMID 39918841 · DOI 10.1164/rccm.202407-1474oc

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Trials by the same sponsor.

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