Who is sponsoring NCT04166981?

NCT04166981 is sponsored by Spine Centre of Southern Denmark.

What drugs are being tested in NCT04166981?

Interventions in NCT04166981: Instrumented posterolateral spine fusion., Non-instrumented posterolateral spine fusion..

What condition does NCT04166981 study?

NCT04166981 studies Spinal Stenosis, Spondylolisthesis Degenerative, Spinal Fusion.

Is NCT04166981 still recruiting?

NCT04166981 is currently completed. Last updated 31 March 2022.

Last reviewed 2022-03-31 · How we verify

NCT04166981

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Instr. vs. Non-instr. Posterolateral Spinal Fusion in Patients With Spinal Stenosis and Degenerative Listhesis

Completed NA Last updated 31 March 2022

What this trial tests

NA trial testing Instrumented posterolateral spine fusion. in Spinal Stenosis in 104 participants. Completed in 1 December 2021.

Timeline

1 January 2017

Primary endpoint
1 December 2021

1 December 2021

Quick facts

Lead sponsor	Spine Centre of Southern Denmark
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	104
Start date	1 January 2017
Primary completion	1 December 2021
Estimated completion	1 December 2021
Sites	1 location across Denmark

Drugs / interventions tested

Instrumented posterolateral spine fusion.
Non-instrumented posterolateral spine fusion.

Conditions studied

Spinal Stenosis — all drugs for Spinal Stenosis →
Spondylolisthesis Degenerative — all drugs for Spondylolisthesis Degenerative →
Spinal Fusion — all drugs for Spinal Fusion →

Sponsor

Spine Centre of Southern Denmark

Who can join

60 and older, any sex, with Spinal Stenosis or Spondylolisthesis Degenerative. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to determine, in patients with grade 1 degenerative spondylolisthesis with spinal stenosis, if decompression and lumbar spinal fusion with, or without supplementary pedicle screw fixation yields an improved patient reported outcome.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Cost-Effectiveness of ABM/P-15 Versus Allograft in Degenerative Spondylolisthesis Surgery : Ten-Year Follow-Up on a Randomized Controlled Trial.
Andresen AK, Carreon LY, Andersen MØ, Nielsen L, et al · · 2026 · PMID 41802428 · DOI 10.1097/brs.0000000000005680

Verify or expand the search:

Other recruiting trials for Spinal Stenosis

Currently open trials in the same condition.

NCT07348419 — Quadro-Iliac vs Thoracolumbar Interfascial Plane Block for Analgesia After Single-Level Lumbar Disc Surgery · NA · recruiting
NCT06233617 — Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Spine Surgery · Phase 4 · recruiting
NCT06950853 — ESCAPE : Evaluation of Spinal Conservation by Endoscopic Procedures to Avoid Fusion · recruiting
NCT06120231 — Pulse-Width Modulation · NA · recruiting
NCT06140927 — Effect of Ketamine on Intraoperative Motor Evoked Potentials · Phase 3 · recruiting

Other Spine Centre of Southern Denmark trials

Trials by the same sponsor.

NCT06141187 — Percutaneous Vertebroplasty Vs. Sham for Osteoporotic Vertebral Compression Fractures Focusing on Pain and Economy. · NA · recruiting
NCT05115227 — Long-term Multidisciplinary Team-based Management of Back Pain · NA · completed
NCT04406987 — Instability in the Lumbar Spine of Patients With Age Related Changes and Narrowing of the Spinal Canal (Spinal Stenosis) · completed
NCT04888026 — Impact on Pain Sensitivity of Clinical Interaction · NA · completed
NCT04533217 — Examination of Vertebroplasty in Addition to Regular Treatment of Patients With Multiple Myeloma. · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04166981 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Spine Centre of Southern Denmark
Last refreshed: 31 March 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04166981.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing