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NCT04533217
Examination of Vertebroplasty in Addition to Regular Treatment of Patients With Multiple Myeloma.
NA trial testing Vertebroplasty in Vertebral Fracture in 90 participants. Currently enrolling.
31 July 2025
Quick facts
| Lead sponsor | Spine Centre of Southern Denmark |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 90 |
| Start date | 29 March 2021 |
| Primary completion | 31 July 2025 |
| Estimated completion | 31 July 2026 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Vertebroplasty
Conditions studied
- Vertebral Fracture — all drugs for Vertebral Fracture →
- Multiple Myeloma — all drugs for Multiple Myeloma →
Sponsor
Spine Centre of Southern Denmark
Who can join
18 and older, any sex, with Vertebral Fracture or Multiple Myeloma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients with newly diagnosed or known multiple myeloma with newly diagnosed vertebral lesion(s) will be invited to participate in a cross-sectoral randomized controlled trial. The trial will compare two groups of patients which either receive regular medical treatment of their vertebral lesion(s) or vertebroplasty in addition to regular medical treatment. Our goal is to investigate the effectiveness of vertebroplasty and determine the role of surgical treatment in the overall treatment of patients with multiple myeloma and vertebral lesion(s).
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Novel Developments in the Treatment of Multiple Myeloma-Associated Bone Disease.
Johansen M, Levring MB, Stokbro K, Diaz-delCastillo M, et al · · 2023 · cited 4× · PMID 38067289 · DOI 10.3390/cancers15235585 -
Vertebroplasty in patients with multiple myeloma with vertebral compression fractures: protocol for a single-blind randomised controlled trial.
Wickstroem LA, Carreon L, Lund T, Abildgaard N, et al · · 2021 · cited 3× · PMID 34489267 · DOI 10.1136/bmjopen-2020-045854
Verify or expand the search:
- PubMed search for NCT04533217
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other recruiting trials for Vertebral Fracture
Currently open trials in the same condition.
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Other Spine Centre of Southern Denmark trials
Trials by the same sponsor.
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- NCT05115227 — Long-term Multidisciplinary Team-based Management of Back Pain · NA · completed
- NCT04406987 — Instability in the Lumbar Spine of Patients With Age Related Changes and Narrowing of the Spinal Canal (Spinal Stenosis) · completed
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04533217 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Spine Centre of Southern Denmark
- Last refreshed: 3 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04533217.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing