NCT04154059 is a NA clinical trial of Intervention Group in Knee Osteoarthritis, sponsored by Universidade Federal de Sao Carlos.

Who is sponsoring NCT04154059?

NCT04154059 is sponsored by Universidade Federal de Sao Carlos.

What drugs are being tested in NCT04154059?

Interventions in NCT04154059: Intervention Group.

What condition does NCT04154059 study?

NCT04154059 studies Knee Osteoarthritis.

Is NCT04154059 still recruiting?

NCT04154059 is currently terminated. Last updated 2 April 2025.

Last reviewed 2025-04-02 · How we verify

NCT04154059

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Strengthening Program for Foot-ankle Muscles in People With Knee Osteoarthritis

Terminated NA Last updated 2 April 2025

What this trial tests

NA trial testing Intervention Group in Knee Osteoarthritis in 30 participants. Terminated before completion.

Timeline

27 January 2020

Primary endpoint
1 March 2020

4 August 2023

Quick facts

Lead sponsor	Universidade Federal de Sao Carlos
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	30
Start date	27 January 2020
Primary completion	1 March 2020
Estimated completion	4 August 2023
Sites	1 location across Brazil

Drugs / interventions tested

Intervention Group — full drug profile →

Conditions studied

Knee Osteoarthritis — all drugs for Knee Osteoarthritis →

Sponsor

Universidade Federal de Sao Carlos

Who can join

Adults 40 to 75, any sex, with Knee Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main objective of this trial is To evaluate the effect of an ankle and foot muscle strengthening program on pain, analgesic consumption, functionality, and lower limb biomechanics during gait in individuals with knee osteoarthritis.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Exercise for osteoarthritis of the knee.
Lawford BJ, Hall M, Hinman RS, Van der Esch M, et al · · 2024 · cited 37× · PMID 39625083 · DOI 10.1002/14651858.cd004376.pub4
Effects of a foot-ankle strengthening programme on clinical aspects and gait biomechanics in people with knee osteoarthritis: protocol for a randomised controlled trial.
Dantas G, Sacco ICN, Dos Santos AF, Watari R, et al · · 2020 · cited 5× · PMID 32978204 · DOI 10.1136/bmjopen-2020-039279
Effects of a foot-ankle muscle strengthening program on pain and function in individuals with knee osteoarthritis: a randomized controlled trial.
Dantas GAF, Sacco ICN, Ferrari AV, Matias AB, et al · · 2023 · cited 3× · PMID 37603935 · DOI 10.1016/j.bjpt.2023.100531

Verify or expand the search:

Other trials of Intervention Group

Trials testing the same drug.

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NCT07485400 — Aerobic Interval vs Continuous Training on Heart Rate-Power Decoupling in Ischemic Heart Disease · NA · not yet recruiting
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NCT07306221 — Effect of Visual-Guided Balance Training on Knee Motor Function and Biomechanical Characteristics After ACL Reconstructi · NA · recruiting

Other recruiting trials for Knee Osteoarthritis

Currently open trials in the same condition.

NCT06906939 — A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression · EARLY_PHASE1 · recruiting
NCT05823727 — Effects of Collagen Peptide Supplementation on Connective Tissue Remodeling, Functional Outcomes, and Wound Healing Afte · NA · recruiting
NCT07370480 — Knee Osteoarthritis and Thermal Spa Treatment · NA · recruiting
NCT07507175 — Gastrocnemius Myofascial Release in Females With Knee Osteoarthritis · NA · recruiting
NCT07386600 — Dexamethasone vs Dexmedetomidine for iPACK + ACB in TKA · NA · recruiting

Other Universidade Federal de Sao Carlos trials

Trials by the same sponsor.

NCT06259344 — Pain Science Education Administered in Full or Fractioned Dosage Modes for Temporomandibular Disorders · NA · not yet recruiting
NCT06678698 — Acute Effect of Photobiomodulation in Individuals with Hypertension · NA · recruiting
NCT06866522 — Light Reflection on Human Skin in Whole-Body Photobiomodulation Therapy · NA · recruiting
NCT05996991 — The Impact of Positive, Neutral and Negative Expectation Speech on Manipulative Therapy Effects · NA · unknown
NCT05989815 — Effect of Whole-body Photobiomodulation on Muscular Performance Enhancement. · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04154059 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidade Federal de Sao Carlos
Last refreshed: 2 April 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04154059.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing