NCT04151095 is a NA clinical trial of BFR Exercise Training in Mitochondrial Biogenesis, sponsored by Brendon Gurd, PhD.

Who is sponsoring NCT04151095?

NCT04151095 is sponsored by Brendon Gurd, PhD.

What drugs are being tested in NCT04151095?

Interventions in NCT04151095: BFR Exercise Training, CTL Exercise Training.

What condition does NCT04151095 study?

NCT04151095 studies Mitochondrial Biogenesis.

Is NCT04151095 still recruiting?

NCT04151095 is currently completed. Last updated 26 December 2023.

Last reviewed 2023-12-26 · How we verify

NCT04151095

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Examining The Effect of Blood Flow Restricted Aerobic Training on Mitochondrial Adaptations in Young Healthy Adults

Completed NA Last updated 26 December 2023

What this trial tests

NA trial testing BFR Exercise Training in Mitochondrial Biogenesis in 19 participants. Completed in 13 December 2019.

Timeline

6 May 2019

Primary endpoint
13 December 2019

13 December 2019

Quick facts

Lead sponsor	Brendon Gurd, PhD
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	basic science
Enrollment	19
Start date	6 May 2019
Primary completion	13 December 2019
Estimated completion	13 December 2019
Sites	1 location across Canada

Drugs / interventions tested

BFR Exercise Training
CTL Exercise Training

Conditions studied

Mitochondrial Biogenesis — all drugs for Mitochondrial Biogenesis →

Sponsor

Brendon Gurd, PhD

Who can join

Adults 18 to 30, any sex, with Mitochondrial Biogenesis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This parallel-arm trial study investigates the effects of restricting arterial blood flow during cycling exercise on citrate synthase. Participants will be randomized to either a blood flow restricted or non-blood flow restricted exercise training group. Both groups will complete seven, 30-minute exercise sessions over a 14-day period.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Mitochondrial and cardiovascular responses to aerobic exercise training in supine and upright positions in healthy young adults: a randomized parallel arm trial.
Preobrazenski N, Mladen SPS, Causer E, Menezes E, et al · · 2025 · PMID 40224168 · DOI 10.1515/teb-2025-0002

Verify or expand the search:

Other Brendon Gurd, PhD trials

Trials by the same sponsor.

NCT04295590 — Impact of Augmenting Exercise Intensity vs. Frequency · NA · unknown
NCT03975777 — Time-course of Mitochondrial Biogenic Gene and Protein Expression in Exercised Human Skeletal Muscle · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04151095 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Brendon Gurd, PhD
Last refreshed: 26 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04151095.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing