NCT03975777 is a NA clinical trial of LO in Mitochondrial Biogenesis, sponsored by Brendon Gurd, PhD.

Who is sponsoring NCT03975777?

NCT03975777 is sponsored by Brendon Gurd, PhD.

What drugs are being tested in NCT03975777?

Interventions in NCT03975777: LO, HI.

What condition does NCT03975777 study?

NCT03975777 studies Mitochondrial Biogenesis.

Is NCT03975777 still recruiting?

NCT03975777 is currently status unknown. Last updated 4 March 2020.

Last reviewed 2020-03-04 · How we verify

NCT03975777

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Time-course of Mitochondrial Biogenic Gene and Protein Expression in Exercised Human Skeletal Muscle

Status unknown NA Last updated 4 March 2020

What this trial tests

NA trial testing LO in Mitochondrial Biogenesis in 10 participants. Status unknown.

Timeline

1 June 2019

Primary endpoint
30 April 2020

30 April 2020

Quick facts

Lead sponsor	Brendon Gurd, PhD
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	basic science
Enrollment	10
Start date	1 June 2019
Primary completion	30 April 2020
Estimated completion	30 April 2020
Sites	1 location across Canada

Drugs / interventions tested

Conditions studied

Mitochondrial Biogenesis — all drugs for Mitochondrial Biogenesis →

Sponsor

Brendon Gurd, PhD

Who can join

Adults 18 to 30, male only, with Mitochondrial Biogenesis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study examines the impact of exercise intensity on the 12-hour time-course of mitochondrial biogenic gene and protein expression in human skeletal muscle. Briefly, participants will perform two experimental sessions involving an acute bout of work-matched low- or high-intensity interval cycling exercise in a randomized crossover fashion, two weeks apart. Skeletal muscle biopsies will be obtained from the vastus lateralis (3 from each leg) before and 1, 3, 6, 9, and 12 hours post-exercise. Changes in the expression of various transcription factors and mitochondrial proteins will be examined at the mRNA and protein level to determine the time-course of changes in these factors differs between exercise protocols of different intensities.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other Brendon Gurd, PhD trials

Trials by the same sponsor.

NCT04295590 — Impact of Augmenting Exercise Intensity vs. Frequency · NA · unknown
NCT04151095 — Examining The Effect of Blood Flow Restricted Aerobic Training on Mitochondrial Adaptations in Young Healthy Adults · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03975777 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Brendon Gurd, PhD
Last refreshed: 4 March 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03975777.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing