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NCT04149301
Subtalar Joint Morphology and Foot Deformity in Cerebral Palsy
trial testing 3D gait analysis in Cerebral Palsy in 23 participants. Completed in 31 December 2023.
1 November 2023
Quick facts
| Lead sponsor | Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 23 |
| Start date | 1 April 2022 |
| Primary completion | 1 November 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- 3D gait analysis
- MRI scan
Conditions studied
- Cerebral Palsy — all drugs for Cerebral Palsy →
Sponsor
Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust — full company profile →
Who can join
Adults 7 to 16, any sex, with Cerebral Palsy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cerebral palsy (CP) is a major cause of disability. Many children with CP develop foot deformities as they grow and these can become painful, adversely affecting their quality of life. The research team has previously studied foot morphology and biomechanics, including analysis of the subtalar joint and has successfully located the joint axis from MRI scans. In this project 25 children will be recruited (15 children with CP and 10 unimpaired control subjects). Each child will attend for a single visit, when they will undergo an MRI scan (with the foot loaded and unloaded) to measure the morphology of the ankle and foot, in particular the subtalar axis alignment. This has not been done before in CP. Each child will have an instrumented gait analysis and musculoskeletal modelling techniques will be used to study the biomechanical action of the external ground reaction force and internal muscle forces. The potential of these forces to rotate the subtalar joint and deform the foot will be assessed, resulting in new insights into potential mechanisms of foot deformity. The children will then be categorised to identify those most at risk, leading to personalised screening measures and treatment strategies in the future.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04149301
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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- NCT07342348 — Using Power Mobility Training to Promote Arm & Hand Function in Children With Cerebral Palsy · NA · recruiting
Other Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust trials
Trials by the same sponsor.
- NCT07102563 — Biological Link Between Anxiety and Outcomes Post Knee Arthroplasty · not yet recruiting
- NCT06895239 — Elbow Arthroplasty and Patient Reported Post-operative Activities · not yet recruiting
- NCT07060469 — Comparison Between Anatomic Shoulder Arthroplasty, Hemiarthroplasty, and Reverse Shoulder Arthroplasty. · not yet recruiting
- NCT07014306 — The Oswestry Metabolic BONE Cohort · not yet recruiting
- NCT06782269 — Incidence of Subtalar Joint Fusion After Isolated Ankle Fusion · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04149301 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
- Last refreshed: 29 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04149301.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing