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NCT03840252: PARKONTHEWAY
Progression of Striatal and Extrastriatal Degeneration in PD and PSP Patients
NA trial testing 3D gait analysis in Parkinson Disease (PD) in 78 participants. Completed in 31 July 2019.
25 July 2019
Quick facts
| Lead sponsor | IRCCS San Raffaele Roma |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 78 |
| Start date | 23 September 2015 |
| Primary completion | 25 July 2019 |
| Estimated completion | 31 July 2019 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- 3D gait analysis
- rsfMRI
- Montreal Cognitive assesment (MoCA)
Conditions studied
- Parkinson Disease (PD) — all drugs for Parkinson Disease (PD) →
- Paralysis; Supranuclear — all drugs for Paralysis; Supranuclear →
Sponsor
IRCCS San Raffaele Roma — full company profile →
Who can join
Adults 20 to 80, any sex, with Parkinson Disease (PD) or Paralysis; Supranuclear. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This longitudinal study aims to research cognitive and gait phenotypes of Parkinson's disease and Supranuclear Palsy as well as to provide markers to track diseases progression using a multi-modality approach based on 3D-gait analysis and MR Imaging. Specifically, this study want to identify cognitive pattern and gait-related cerebral diffusion/functional connectivity in PD and PSP patients and to verify their progression over a period of 18 months. In summary, the current protocol proposed to investigate the following issues: * to perform a multifactorial quantitative analysis of outcomes for PD and PSP compared to a control group in order to categorize cognitive and gait pattern in the group of patients and verify if the gait can be useful as discriminator for diagnosis. * to analyze whether diffusion and resting-state functional connectivity indices are correlated with clinical disease severity scores and motor scores and how they change over time (18 months later).
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03840252
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of 3D gait analysis
Trials testing the same drug.
- NCT04149301 — Subtalar Joint Morphology and Foot Deformity in Cerebral Palsy · completed
Other recruiting trials for Parkinson Disease (PD)
Currently open trials in the same condition.
- NCT07176286 — 18F-mFBG Cardiac Uptake With Lewy Body Dementia · Phase 2 · recruiting
- NCT07495462 — Effect of Motor Imagery Added to Rehabilitation on Balance and Kinesiophobia in Patients With Parkinson's Disease · NA · recruiting
- NCT07308795 — The Ultrasonographic Evaluation of Abdominal Accessory Respiratory Muscle Thickness in Patients With Parkinson's Disease · recruiting
- NCT07302386 — Exercise Management in Parkinson's Disease · NA · recruiting
- NCT07157345 — Testing if PDR-001 Can Safely and Effectively Remove Harmful Brain Protein in Parkinson's Disease · Phase 1 · recruiting
Other IRCCS San Raffaele Roma trials
Trials by the same sponsor.
- NCT07431671 — Feeding Disorders in Children · NA · recruiting
- NCT07097103 — Parkinson's Research In Metagenomic Early Stage Biomarkers · NA · not yet recruiting
- NCT06868953 — Use of the Combination of Sumatriptan and Naproxen in the Acute Treatment of Migraine: Real World Evidence Study · not yet recruiting
- NCT06839482 — Robotic Rehabilitation of the Upper Limb in Subacute Stroke · NA · recruiting
- NCT06915584 — Drug Management in Heart Failure · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03840252 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by IRCCS San Raffaele Roma
- Last refreshed: 10 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03840252.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing