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NCT04147962: LACRYSTIM
Intense Pulsed Light in Meibomian Gland Dysfunctions
trial testing intense pulsed light (usual practice) in Dry Eye Syndromes in 45 participants. Completed in 1 June 2020.
1 June 2020
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire de Saint Etienne |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 45 |
| Start date | 25 October 2019 |
| Primary completion | 1 June 2020 |
| Estimated completion | 1 June 2020 |
| Sites | 1 location across France |
Drugs / interventions tested
- intense pulsed light (usual practice)
Conditions studied
- Dry Eye Syndromes — all drugs for Dry Eye Syndromes →
- Meibomian Gland Dysfunction — all drugs for Meibomian Gland Dysfunction →
Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Who can join
18 and older, any sex, with Dry Eye Syndromes or Meibomian Gland Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Dry eye disease (DED) is an extremely common disease whose meibomian gland dysfunction is the main etiology. Polychromatic intense pulsed light (IPL) is a promising new therapeutic alternative but few clinical data have been published. A new IPL device has recently been marketed: LACRYSTIM (QUANTEL, France). The investigators have been using it in our clinical practice since June 2019. The investigators present a retrospective study on our first clinical results.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A retrospective study of the efficacy of intense pulsed light delivered by the Lacrystim® for meibomian gland dysfunction therapy.
Trone MC, Garcin T, Ollier E, Thuret G, et al · · 2022 · cited 7× · PMID 35933379 · DOI 10.1186/s12886-022-02531-7
Verify or expand the search:
- PubMed search for NCT04147962
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other Centre Hospitalier Universitaire de Saint Etienne trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04147962 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Saint Etienne
- Last refreshed: 13 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04147962.
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