Who is sponsoring NCT04133987?

NCT04133987 is sponsored by National Taiwan University Hospital.

What drugs are being tested in NCT04133987?

Interventions in NCT04133987: Tetravalent live attenuated dengue vaccine admixture TV005, Placebo.

Is NCT04133987 still recruiting?

NCT04133987 is currently completed. Last updated 18 January 2023.

Last reviewed 2023-01-18 · How we verify

NCT04133987

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Trial of the Safety and Immunogenicity of a Tetravalent Dengue Virus Vaccine Admixture TV005 in the Elderly Aged 50-70 Years in Taiwan

Completed Phase 2 Last updated 18 January 2023

What this trial tests

Phase 2 trial testing Tetravalent live attenuated dengue vaccine admixture TV005 in Dengue in 252 participants. Completed in 30 September 2022.

Timeline

15 October 2018

Primary endpoint
30 April 2020

30 September 2022

Quick facts

Lead sponsor	National Taiwan University Hospital
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	252
Start date	15 October 2018
Primary completion	30 April 2020
Estimated completion	30 September 2022
Sites	1 location across Taiwan

Drugs / interventions tested

Tetravalent live attenuated dengue vaccine admixture TV005 — full drug profile →
Placebo

Conditions studied

Dengue — all drugs for Dengue →

Sponsor

National Taiwan University Hospital

Who can join

Adults 50 to 70, any sex, with Dengue. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Phase II, randomized, double-blind, placebo-controlled study of the safety and immunogenicity of the recombinant live attenuated tetravalent dengue virus vaccine admixture TV005 in the elderly in Taiwan

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Current Development and Challenges of Tetravalent Live-Attenuated Dengue Vaccines.
Hou J, Ye W, Chen J. · · 2022 · cited 46× · PMID 35281026 · DOI 10.3389/fimmu.2022.840104
Recommendations for dengue vaccine implementation in the elderly population.
Giang NNT, Taylor-Robinson AW. · · 2025 · cited 1× · PMID 39963378 · DOI 10.1177/25151355251321718

Verify or expand the search:

Other recruiting trials for Dengue

Currently open trials in the same condition.

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NCT06894901 — Impact of IIT-SIT on Dengue Clusters · NA · recruiting
NCT07158190 — Evaluation of T-cell Responses After Vaccination With the Attenuated Tetravalent Dengue Vaccine (Takeda). · active not recruiting

Other National Taiwan University Hospital trials

Trials by the same sponsor.

NCT06936917 — Timing for Computed Tomography and Post-Resuscitation Care on Short-Term Outcomes in Out-of-Hospital Cardiac Arrest · not yet recruiting
NCT05396222 — A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar · NA · not yet recruiting
NCT07532356 — Integrating Tumor Genomics and Urinary Exosomal Proteomics to Establish a Multi-Layer Biomarker Framework for Early Risk · not yet recruiting
NCT07317310 — The NTU JO-SMART Study · NA · not yet recruiting
NCT07382024 — Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04133987 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
Last refreshed: 18 January 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04133987.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing