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NCT04118101
Erector Spinae Plane Block
Phase 2, PHASE3 trial testing ESPB block in Post Operative Pain in 46 participants. Completed in 15 February 2021.
10 December 2020
Quick facts
| Lead sponsor | Theodor Bilharz Research Institute |
|---|---|
| Phase | Phase 2, PHASE3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 46 |
| Start date | 25 October 2019 |
| Primary completion | 10 December 2020 |
| Estimated completion | 15 February 2021 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- ESPB block — full drug profile →
- control
Conditions studied
- Post Operative Pain — all drugs for Post Operative Pain →
Sponsor
Theodor Bilharz Research Institute
Who can join
Adults 18 to 60, any sex, with Post Operative Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Erector spinae plane block (ESPB) is a relatively new plane block that was first described by Forero et al. in 2016, to manage persistent neuropathic pain following malunited rib fracture and persistent post-thoracotomy neuropathic pain.It's a relatively simple, ultrasound guided block in which the local anesthetic drugs are injected in the plane between the erector spinae muscle and the vertebral transverse process.This allows the injected local anesthetics to block the ventral and dorsal rami of the spinal nerves in the paravertebral area. The literature reveals successful case reports denoting the use of ESPB for pain control in cases of acute kidney transplant,percutaneous nephrolithomy, abdominal surgeries including laparoscopic and open nephrectomy, and nephrectomy in the pediatric population. The aim of this prospective randomized controlled study is to investigate the efficacy of ESPB for pain control in adult patients undergoing open renal surgery through a flank incision with respect to pain scores, postoperative analgesia consumption and patient satisfaction.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04118101
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Post Operative Pain
Currently open trials in the same condition.
- NCT06779604 — Dexmedetomidine and Dexamethasone Added as Adjuvant Infraclavicular Brachial Plexus Block in Upper Limb Surgery · recruiting
- NCT07223580 — A Study Of Corticosteroid On Postoperative Pain After Ureteroscopy For Urinary Calculi · Phase 4 · recruiting
- NCT07227064 — Methadone in THA for Post-op Pain and Opioid Reduction · Phase 3 · recruiting
- NCT07226076 — Methadone in TKA for Post-op Pain and Opioid Reduction · Phase 3 · recruiting
- NCT07349810 — Post Operative Infusion Pump Pain Study · Phase 4 · recruiting
Other Theodor Bilharz Research Institute trials
Trials by the same sponsor.
- NCT06872138 — S100A8 in Serum and Urine as a New Biomarker in Lupus Nephritis · completed
- NCT07262398 — Unilateral Intrathecal Bupivacaine Versus Prilocaine on Postoperative Spontaneous Voiding · Phase 4 · completed
- NCT06414395 — The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients U · Phase 4 · recruiting
- NCT06541613 — Bilateral External Oblique Intercostal Plane Block in Laparoscopic Cholecystectomy · Phase 4 · completed
- NCT07481812 — Prolapsed Hemorrhoids: Assessment of Various Surgical Modalities · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04118101 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Theodor Bilharz Research Institute
- Last refreshed: 2 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04118101.
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