NCT04115592 is a NA clinical trial of Cocoa butter in Diabetes Mellitus, Type 2, sponsored by Singapore Institute of Food and Biotechnology Innovation.

Who is sponsoring NCT04115592?

NCT04115592 is sponsored by Singapore Institute of Food and Biotechnology Innovation.

What drugs are being tested in NCT04115592?

Interventions in NCT04115592: Cocoa butter, Cocoa butter oleogel, Sal seed oil, Sal seed oleogel.

What condition does NCT04115592 study?

NCT04115592 studies Diabetes Mellitus, Type 2, Cardiovascular Risk Factor.

Is NCT04115592 still recruiting?

NCT04115592 is currently completed. Last updated 20 August 2021.

Last reviewed 2021-08-20 · How we verify

NCT04115592

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Different States of Lipid in Food on Glycaemia, Lipaemia and Insulinaemia.

Completed NA Last updated 20 August 2021

What this trial tests

NA trial testing Cocoa butter in Diabetes Mellitus, Type 2 in 19 participants. Completed in 9 March 2020.

Timeline

20 February 2019

Primary endpoint
16 January 2020

9 March 2020

Quick facts

Lead sponsor	Singapore Institute of Food and Biotechnology Innovation
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	other
Enrollment	19
Start date	20 February 2019
Primary completion	16 January 2020
Estimated completion	9 March 2020
Sites	1 location across Singapore

Drugs / interventions tested

Cocoa butter
Cocoa butter oleogel
Sal seed oil
Sal seed oleogel

Conditions studied

Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →
Cardiovascular Risk Factor — all drugs for Cardiovascular Risk Factor →

Sponsor

Singapore Institute of Food and Biotechnology Innovation

Who can join

Adults 21 to 40, male only, with Diabetes Mellitus, Type 2 or Cardiovascular Risk Factor. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to investigate if the application of lipid in various form (i.e. liquid and solid) affects glycaemia, lipaemia and insulinaemia. In addition, this study aims to test the lipidemic effects of the use of vegetable oil as a substitute in the application for making chocolate confectionery.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effects of Cocoa Butter and Cocoa Butter Equivalent in a Chocolate Confectionery on Human Blood Triglycerides, Glucose and Insulin.
Quek RYC, Peh EWY, Henry CJ. · · 2020 · cited 8× · PMID 32276375 · DOI 10.3390/foods9040455

Verify or expand the search:

Other recruiting trials for Diabetes Mellitus, Type 2

Currently open trials in the same condition.

NCT07415954 — A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 · Phase 2 · recruiting
NCT07532863 — A Real-world Study to Investigate Cardiovascular Risk Profile Among Newly Diagnosed Type 2 Diabetes Mellitus (T2DM) Part · recruiting
NCT07336329 — Continuous Glucose Monitoring in Non-Insulin Treated Type 2 Diabetes: Continuous vs. Periodic Use · NA · recruiting
NCT07242469 — A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006) · Phase 1 · recruiting
NCT07444203 — Transformative Research in Diabetic Nephropathy 2.0 · recruiting

Other Singapore Institute of Food and Biotechnology Innovation trials

Trials by the same sponsor.

NCT07397754 — Sodium-rich COndiments Unifying Health and Taste · NA · recruiting
NCT06691126 — Pharmacokinetic Study of Terpinolene in Healthy Subjects (PKT Study) · NA · completed
NCT06421194 — Functional and Nutritional Plant-based Mixed Protein Study (FuN Protein Study) · NA · recruiting
NCT06119035 — Insulin Modelling Based on Plasma Glucose Measures Via a Minimally-Invasive Glucose Sensor · NA · completed
NCT06640335 — The Effects of Vegetable Preloading on Postprandial Glycemia, Insulinaemia and Gastric Emptying · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04115592 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Singapore Institute of Food and Biotechnology Innovation
Last refreshed: 20 August 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04115592.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing