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NCT04109560
HFNC and Acute Hypercapnic Respiratory Failure
trial in High Flow Oxygen Therapy in 40 participants. Completed in 30 September 2019.
30 September 2019
Quick facts
| Lead sponsor | Argentinian Intensive Care Society |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 40 |
| Start date | 1 August 2018 |
| Primary completion | 30 September 2019 |
| Estimated completion | 30 September 2019 |
| Sites | 1 location across Argentina |
Conditions studied
- High Flow Oxygen Therapy — all drugs for High Flow Oxygen Therapy →
- Acute Hypercapnic Respiratory Failure — all drugs for Acute Hypercapnic Respiratory Failure →
- COPD Exacerbation — all drugs for COPD Exacerbation →
Sponsor
Argentinian Intensive Care Society
Who can join
18 and older, any sex, with High Flow Oxygen Therapy or Acute Hypercapnic Respiratory Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
High-flow nasal cannula (HFNC) enables delivering humidified gas at high-flow rates controlling the oxygen inspired fraction (FiO2). Its efficacy has been demonstrated in hypoxemic acute respiratory failure. However, little is known about its use in hypercapnic acute respiratory failure (ARF). Therefore, we aimed to evaluate the effect of using HFNC through "Precision Flow" equipment as first line of ventilatory support for COPD patients with hypercapnic acute respiratory failure.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
High-Flow Oxygen Therapy Application in Chronic Obstructive Pulmonary Disease Patients With Acute Hypercapnic Respiratory Failure: A Multicenter Study.
Plotnikow GA, Accoce M, Fredes S, Tiribelli N, et al · · 2021 · cited 13× · PMID 33615235 · DOI 10.1097/cce.0000000000000337
Verify or expand the search:
- PubMed search for NCT04109560
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Argentinian Intensive Care Society trials
Trials by the same sponsor.
- NCT07017205 — Microaspiration and Endotracheal Tubes · NA · not yet recruiting
- NCT06837402 — Epidemiology of Non- Invasive Mechanical Ventilation in Argentina: a Multicenter Observational Study · enrolling by invitation
- NCT06824220 — Effect of High-Flow Tracheal Oxygen on EELI · NA · active not recruiting
- NCT06674629 — Asymmetrical High Flow Nasal Cannula and End-Expiratory Lung Impedance · completed
- NCT06662201 — Association Between P0.1 and Extubation Failure in Adult Patients With Acute Hypoxemic Respiratory Failure. A Multicente · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04109560 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Argentinian Intensive Care Society
- Last refreshed: 23 October 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04109560.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing