Who is sponsoring NCT04082676?

NCT04082676 is sponsored by B.P. Koirala Institute of Health Sciences.

What drugs are being tested in NCT04082676?

Interventions in NCT04082676: Hyperbaric bupivacaine spinal, Hyperbaric bupivacaine spinal.

What condition does NCT04082676 study?

NCT04082676 studies Maternal Hypotension After Spinal Anesthesia.

Is NCT04082676 still recruiting?

NCT04082676 is currently completed. Last updated 22 March 2022.

Last reviewed 2022-03-22 · How we verify

NCT04082676

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Height Versus Height and Weight Based Spinal Bupivacaine on Maternal Haemodynamics for Elective Cesarean in Short Stature Patients

Completed Phase 4 Last updated 22 March 2022

What this trial tests

Phase 4 trial testing Hyperbaric bupivacaine spinal in Maternal Hypotension After Spinal Anesthesia in 112 participants. Completed in 1 September 2021.

Timeline

30 November 2019

Primary endpoint
1 September 2021

1 September 2021

Quick facts

Lead sponsor	B.P. Koirala Institute of Health Sciences
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	112
Start date	30 November 2019
Primary completion	1 September 2021
Estimated completion	1 September 2021
Sites	1 location across Nepal

Drugs / interventions tested

Hyperbaric bupivacaine spinal — full drug profile →
Hyperbaric bupivacaine spinal — full drug profile →

Conditions studied

Maternal Hypotension After Spinal Anesthesia — all drugs for Maternal Hypotension After Spinal Anesthesia →

Sponsor

B.P. Koirala Institute of Health Sciences

Who can join

Adults 18 to 40, female only, with Maternal Hypotension After Spinal Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Doses of intrathecal bupivacaine based on patients either height or height and weight has shown to lower the risk of maternal hypotension with similar quality of anesthesia compared to conventional doses. In clinical practice there is a tendency of reducing the dose of bupivacaine as either low fixed dose or using the doses based on either height and weight or height (0.06mg/cm) alone in parturient with short stature. However, there is lack of evidence regarding the appropriate dose required in this group of patients. Therefore, our aim is to compare the height versus height and weight based intrathecal bupivacaine dose for elective caesarean on maternal haemodynamics in short stature patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effect of height versus height/weight-based spinal bupivacaine on maternal hemodynamics for elective cesarean in short stature patients: a randomized clinical trial.
Subedi A, Thapa P, Prajapati R, Schyns-van den Berg AMJV. · · 2023 · cited 2× · PMID 37709952 · DOI 10.1007/s00540-023-03252-x

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04082676 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by B.P. Koirala Institute of Health Sciences
Last refreshed: 22 March 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04082676.

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