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NCT04076475: NMES
Neuromuscular Electrical Stimulation in Patients With Prolonged Mechanical Ventilation
NA trial testing neuromuscular electrical stimulation in Prolonged Mechanical Ventilation in 8 participants. Completed in 31 January 2021.
31 January 2021
Quick facts
| Lead sponsor | Chang Gung University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 8 |
| Start date | 25 February 2019 |
| Primary completion | 31 January 2021 |
| Estimated completion | 31 January 2021 |
| Sites | 2 locations across Taiwan |
Drugs / interventions tested
- neuromuscular electrical stimulation
Conditions studied
- Prolonged Mechanical Ventilation — all drugs for Prolonged Mechanical Ventilation →
Sponsor
Chang Gung University
Who can join
20 and older, any sex, with Prolonged Mechanical Ventilation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prolonged mechanical ventilation has been defined as the need for \>21 days. The muscle weakness occurred most commonly in patients with PMV and resulted in increasing time to wean from mechanical ventilation, and longer stay in hospital. Neuromuscular electrical stimulation (NMES) involves applying a stimuli to skeletal muscle, to trigger muscle contraction, and it can be used for the recovery of muscle mass and muscle strength following prolonged immobilization. NMES also improve microcirculation and systemic circulation in patients with cardiopulmonary diseases. The purposes of this study: 1. to examine the acute effects of NMES on the microcirculation, physiologic response and metabolic demand in patients with PMV. 2. to investigate the training effects of NMES on microcirculation, muscle strength and weaning outcomes in patients with PMV. METHODS: Subjects with PMV are recruited and are randomly assigned into NMES (n=20) or control group (n=20).The NMES group receive daily NMES for 30 min/session for 10 days. The assessment of muscle strength and weaning profile were performed before and after intervention. During the first and the last NMES session, the status of microcirculation and local muscle tissue oxygenation will be measured by NIRS, and the metabolic status will be measured by IC. The ventilator weaning rate and length of stay in RCC will be recorded.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04076475
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Related trials
Other trials of neuromuscular electrical stimulation
Trials testing the same drug.
- NCT06302946 — Effect of Neuromuscular Stimulation and Mindfulness Exercise in Patients With Stroke · NA · recruiting
- NCT06873022 — EMG Biofeedback and NMES of Deltoid in Patients With rTSA · NA · recruiting
- NCT07161648 — Use of Neuromuscular Electrical Stimulation to Prevent Exercise Resistance · NA · recruiting
- NCT06409611 — MUSCLE EFFECTS OF NEUROMUSCULAR ELECTROSTIMULATION IN MECHANICALLY VENTILATED PATIENTS IN AN ICU · NA · recruiting
- NCT07415785 — NMES Plus Conventional Therapy for Stroke Dysphagia · NA · completed
Other recruiting trials for Prolonged Mechanical Ventilation
Currently open trials in the same condition.
- NCT07177183 — Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure · NA · recruiting
- NCT06125210 — Application of Early Bundle Management of Mechanical Ventilation to Prevent Ventilator Dependence in Children · NA · recruiting
- NCT05634135 — Lung Ventilation and Perfusion in Different Phenotypes of Chronic Critical Illness With Prolonged Mechanical Ventilation · recruiting
Other Chang Gung University trials
Trials by the same sponsor.
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- NCT05953948 — Effectiveness of Intelligent Case Manage Platform in Liver Transplant Recipients · NA · enrolling by invitation
- NCT06464640 — Efficacy of the "Living With Type 1 Diabetes to Grown-Up" Interactive Podcast Program · NA · not yet recruiting
- NCT06392945 — Effects of Rhythmic Auditory Cueing Augments Cognitive Treadmill Walking Training in Individuals With Chronic Stroke · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04076475 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chang Gung University
- Last refreshed: 28 July 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04076475.
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