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NCT04067830
Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer
Phase 2 trial testing Best Practice in Stage I Lung Cancer AJCC v8 in 220 participants. Currently enrolling.
22 March 2027
Quick facts
| Lead sponsor | Roswell Park Cancer Institute |
|---|---|
| Phase | Phase 2 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 220 |
| Start date | 20 March 2019 |
| Primary completion | 22 March 2027 |
| Estimated completion | 22 March 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Best Practice
- Laparoscopic Surgery
- Quality-of-Life Assessment
- Questionnaire Administration
- Respiratory Muscle Training Device
- Video-Assisted Thoracic Surgery
Conditions studied
- Stage I Lung Cancer AJCC v8 — all drugs for Stage I Lung Cancer AJCC v8 →
- Stage IA1 Lung Cancer AJCC v8 — all drugs for Stage IA1 Lung Cancer AJCC v8 →
- Stage IA2 Lung Cancer AJCC v8 — all drugs for Stage IA2 Lung Cancer AJCC v8 →
- Stage IA3 Lung Cancer AJCC v8 — all drugs for Stage IA3 Lung Cancer AJCC v8 →
Sponsor
Roswell Park Cancer Institute
Who can join
18 and older, any sex, with Stage I Lung Cancer AJCC v8 or Stage IA1 Lung Cancer AJCC v8. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This phase II trial studies how well respiratory muscle training before surgery works in preventing lung complications after surgery in patients with stage I-IIIB lung cancer. Patients with lung cancer who choose to undergo surgical resection often have complications after surgery such as pneumonia, unplanned intubations, difficulty breathing and reduced physical functioning, and increased medical costs and a reduced quality of life. Improving pre-surgical pulmonary health through respiratory muscle training may improve respiratory muscle strength, response to surgery, and quality of life after surgery in patients with lung cancer.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Potential Therapeutic Role of Respiratory Muscle Training in Dyspnea Management of Cancer Survivors: A Narrative Review.
Vainshelboim B, Sardesai SD, Bhammar D. · · 2024 · cited 1× · PMID 38751708 · DOI 10.14740/wjon1781
Verify or expand the search:
- PubMed search for NCT04067830
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Roswell Park Cancer Institute trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04067830 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Roswell Park Cancer Institute
- Last refreshed: 5 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04067830.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing