Who is sponsoring NCT05502523?

NCT05502523 is sponsored by Thomas Jefferson University.

What drugs are being tested in NCT05502523?

Interventions in NCT05502523: Pulmonary Artery-First Surgical Technique, Biospecimen Collection.

What condition does NCT05502523 study?

NCT05502523 studies Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8.

Is NCT05502523 still recruiting?

NCT05502523 is currently recruiting now. Last updated 23 January 2026.

Last reviewed 2026-01-23 · How we verify

NCT05502523

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

Recruiting now NA Last updated 23 January 2026

What this trial tests

NA trial testing Pulmonary Artery-First Surgical Technique in Lung Non-Small Cell Carcinoma in 100 participants. Currently enrolling.

Timeline

31 August 2022

Primary endpoint
1 January 2027

1 January 2029

Quick facts

Lead sponsor	Thomas Jefferson University
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	100
Start date	31 August 2022
Primary completion	1 January 2027
Estimated completion	1 January 2029
Sites	4 locations across United States

Drugs / interventions tested

Pulmonary Artery-First Surgical Technique
Biospecimen Collection — full drug profile →

Conditions studied

Lung Non-Small Cell Carcinoma — all drugs for Lung Non-Small Cell Carcinoma →
Stage I Lung Cancer AJCC v8 — all drugs for Stage I Lung Cancer AJCC v8 →
Stage II Lung Cancer AJCC v8 — all drugs for Stage II Lung Cancer AJCC v8 →
Stage III Lung Cancer AJCC v8 — all drugs for Stage III Lung Cancer AJCC v8 →

Sponsor

Thomas Jefferson University

Who can join

18 and older, any sex, with Lung Non-Small Cell Carcinoma or Stage I Lung Cancer AJCC v8. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This clinical trial compares the effect of pulmonary vein-first surgical technique to pulmonary artery-first surgical technique in decreasing circulating tumor cell deoxyribonucleic acid (ctDNA) in patients with stage I-III non-small cell lung cancer. Pulmonary vein first and pulmonary artery first surgical techniques are standard surgical techniques for the division of the blood vessels during lung resection surgery. Pulmonary vein-first surgical technique may reduce the risk of shedding tumor cells during surgery and influence long term overall survival.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Randomized controlled trials in lung cancer surgery: How are we doing?
Wong LY, Li Y, Elliott IA, Backhus LM, et al · · 2024 · cited 1× · PMID 38690441 · DOI 10.1016/j.xjon.2024.01.008

Verify or expand the search:

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Other Thomas Jefferson University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05502523 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Thomas Jefferson University
Last refreshed: 23 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05502523.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing