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NCT04052867
Intravenous Lignocaine Infusion in Laparoscopic Donor Nephrectomy
NA trial testing Lignocaine in Postoperative Pain in 40 participants. Status unknown.
15 July 2021
Quick facts
| Lead sponsor | University of Malaya |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | supportive care |
| Enrollment | 40 |
| Start date | 17 September 2019 |
| Primary completion | 15 July 2021 |
| Estimated completion | 31 July 2021 |
| Sites | 1 location across Malaysia |
Drugs / interventions tested
- Lignocaine — full drug profile →
- Normal saline
Conditions studied
- Postoperative Pain — all drugs for Postoperative Pain →
- Renal Transplantation — all drugs for Renal Transplantation →
- Morphine Adverse Reaction — all drugs for Morphine Adverse Reaction →
Sponsor
University of Malaya
Who can join
18 and older, any sex, with Postoperative Pain or Renal Transplantation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: Administration of morphine as boluses or via a patient controlled analgesic device (PCA) has been the standard practice for donors after nephrectomy. However, administration of morphine is far from being ideal analgesic as it does not provide optimal dynamic pain relief after major surgery, consistently demonstrate little effect on surgical stress response and organ dysfunction with high incidences of postoperative nausea/vomiting, respiratory depression and sedation. Several studies demonstrated perioperative intravenous lignocaine infusion can improve post-operative pain scores and morphine consumption in abdominal surgery. The aim of this study is to identify the effectiveness of intra-operative lignocaine infusion in lowering postoperative pain and reduce postoperative morphine consumption in patients who undergo laparoscopic donor nephrectomy.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04052867
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04052867 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Malaya
- Last refreshed: 30 April 2020
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