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NCT04033627
TCDαβ/CD45RA Haploidentical Transplantation in Children With Leukemia
NA trial testing In Vitro T cells depletion using CliniMCAS system in Relapsed Pediatric ALL in 30 participants. Status unknown.
18 July 2022
Quick facts
| Lead sponsor | Shanghai Children's Medical Center |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 10 November 2020 |
| Primary completion | 18 July 2022 |
| Estimated completion | 8 May 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- In Vitro T cells depletion using CliniMCAS system
Conditions studied
- Relapsed Pediatric ALL — all drugs for Relapsed Pediatric ALL →
- Acute Graft-Versus-Host Disease (Gvhd) Grade IV (Diagnosis) — all drugs for Acute Graft-Versus-Host Disease (Gvhd) Grade IV (Diagnosis) →
- Relapsed Pediatric AML — all drugs for Relapsed Pediatric AML →
Sponsor
Shanghai Children's Medical Center
Who can join
Adults 2 Months to 18, any sex, with Relapsed Pediatric ALL or Acute Graft-Versus-Host Disease (Gvhd) Grade IV (Diagnosis). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a multi-center clinical study in China using CliniMACS TCRα/β+ and CD45RA+ T cell depleted stem cell grafts from haploidentical donors for hematopoietic stem cell transplantation in children.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04033627
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other recruiting trials for Relapsed Pediatric ALL
Currently open trials in the same condition.
- NCT06581081 — Bridging Allogeneic Hematopoietic Stem Cell Transplantation or Not After CD19 CAR - T (S1904) Cell Therapy for r/r B-cel · NA · recruiting
- NCT05334823 — A Study of pCAR-19B in the Treatment of CD19-positive Relapsed/Refractory B-ALL in Children and Adolescents · Phase 2 · recruiting
Other Shanghai Children's Medical Center trials
Trials by the same sponsor.
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- NCT07351955 — Clinical Study on a Novel Strategy of Individualized Non-Invasive Neuromodulation for the Treatment of Tic Disorders in · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04033627 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shanghai Children's Medical Center
- Last refreshed: 29 September 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04033627.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing