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NCT04024553

A Genetic Family Cohort Study of Bipolar Disorder in Chinese Han Population

Status unknown Last updated 18 July 2019
What this trial tests

trial in Bipolar Disorder in 2,520 participants. Status unknown.

Timeline
28 March 2019
Primary endpoint
31 December 2020
31 December 2022

Quick facts

Lead sponsorShanghai Mental Health Center
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment2,520
Start date28 March 2019
Primary completion31 December 2020
Estimated completion31 December 2022
Sites1 location across China

Conditions studied

Sponsor

Shanghai Mental Health Center — full company profile →

Who can join

15 and older, any sex, with Bipolar Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study intends to find out the pathogenic genes of bipolar disorder by collecting the two-phase family of Chinese Han population with the large sample using a family cohort study design, combined with the new generation of high-throughput sequencing technology and Genome-Wide Association Studies (GWAS), Proteomics, bioinformatics analysis, etc., which is expected to be clarified at the genetic level. The pathogenesis of bipolar disorder. At the same time, the investigators will conduct a five-year follow-up of cognitive function, brain function imaging and other major clinical symptoms in patients with bipolar disorder in the core family, and to explore familial bipolar disorder and sporadic biphasic. Differences in the clinical features of the disorder, in order to explore sensitive and specific biomarkers from a multidimensional perspective (cognitive function, brain imaging, genetic features, clinical features, etc.), which may contribute to bipolar disorder in the future. Accurate diagnosis and early identification and prevention have important scientific significance and clinical diagnosis and treatment significance.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Bipolar Disorder

Currently open trials in the same condition.

Other Shanghai Mental Health Center trials

Trials by the same sponsor.

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