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NCT04024176

Gait Analysis in Moderate Hemophiliac Patients (AQM-Hemophile)

Completed NA Last updated 19 October 2020
What this trial tests

NA trial testing Gait analysis in Moderate Hemophilia in 24 participants. Completed in 4 September 2020.

Timeline
29 November 2019
Primary endpoint
4 September 2020
4 September 2020

Quick facts

Lead sponsorNantes University Hospital
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposeprevention
Enrollment24
Start date29 November 2019
Primary completion4 September 2020
Estimated completion4 September 2020
Sites4 locations across France

Drugs / interventions tested

Conditions studied

Sponsor

Nantes University Hospital

Who can join

18 and older, any sex, with Moderate Hemophilia or Arthropathy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The management of moderate hemophilia is less codified than those of severe patients; because these patients are theoretically less likely to bleed and therefore less likely to develop arthropathies. Nowaways, the question arises as to the appropriateness of this "symptomatic" management for the prevention of the occurrence of hemophilic arthropathies. Indeed, a significant number of moderate hemophiliacs seems to develop severe arthropathies that cause significant disability. However, because of the very small proportion of these patients in the total number of hemophiliacs, data are lacking on the impact of arthropathies on this population. The investigators therefore propose to include moderate hemophiliac patients in the study to carry out an evaluation of gait, using a gait analysis to determine the consequences of arthropathies, even sub-clinical ones, according to the duration of the disease's progression. In an associated way, the analysis of different clinical (joint assessment; quality of life score;...), radiological (radiographic; ultrasound (synovial thickness)), biological (level of associated factors ; other associated marker), in order to provide a complete picture of the articular situation in these patients with moderate haemophilia.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Gait Alteration Due to Haemophilic Arthropathies in Patients with Moderate Haemophilia.
    Fouasson-Chailloux A, Leboeuf F, Maugars Y, Trossaert M, et al · · 2022 · cited 7× · PMID 35742774 · DOI 10.3390/ijerph19127527

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Other trials of Gait analysis

Trials testing the same drug.

Other Nantes University Hospital trials

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