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NCT05576064
Is Gait Analysis for Proposed Rotational Deformities a Useful Resource
trial testing Gait analysis in Lower Limb Deformity in 40 participants. Completed in 30 April 2025.
21 April 2023
Quick facts
| Lead sponsor | Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 40 |
| Start date | 21 April 2023 |
| Primary completion | 21 April 2023 |
| Estimated completion | 30 April 2025 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Gait analysis
Conditions studied
- Lower Limb Deformity — all drugs for Lower Limb Deformity →
- Anterior Knee Pain Syndrome — all drugs for Anterior Knee Pain Syndrome →
- Patellofemoral Pain — all drugs for Patellofemoral Pain →
- Rotation; Deformity — all drugs for Rotation; Deformity →
Sponsor
Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust — full company profile →
Who can join
16 and older, any sex, with Lower Limb Deformity or Anterior Knee Pain Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Rotational deformities, such as femoral (thigh bone) and tibial (leg bone) torsion, are established causes of patellofemoral (kneecap joint) pain and instability. Currently, computerized tomography (CT) remains the gold standard assessment tool for measuring the degree of rotational deformity. However, there is disagreement as to the thresholds for surgical correction as it is suggested that some individuals compensate for the deformity better than others. Gait (walking) analysis provides important information of the biomechanical parameters undertaken in the knee joint during dynamic movement. In patients with rotational deformities, several variations from normal gait patterns have previously been described by several authors. Therefore, it is questioned whether these parameters can be correlated with the static features of CT scans, in individuals with rotational deformities. This study aims to determine whether gait analysis is a useful tool in the diagnosis and treatment pathway for rotational abnormalities in patellofemoral pain or instability. A secondary aim of this study will be to assess whether gait analysis can detect a rotational deformity in the lower limb and determine whether the changes seen are proportionate to the level of deformity. Patients to be included in this retrospective study are, adult patients, with presumed rotational deformity of the lower limb, with anterior knee pain, who have been referred to the gait laboratory for assessment, and for CT rotational profiles. Only patients who have given consent to the gait laboratory for their information to be utilised in research will be included. Two researchers will record measures of rotational deformity from the CT images. The gait laboratory assessment includes measurements of biomechanical parameters based on joint movement through the gait cycle - these parameters will be assessed and compared with CT measures for correlation. All research will be conducted at the hospital where the gait laboratory assessment has been performed.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05576064
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Other Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust trials
Trials by the same sponsor.
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- NCT07060469 — Comparison Between Anatomic Shoulder Arthroplasty, Hemiarthroplasty, and Reverse Shoulder Arthroplasty. · not yet recruiting
- NCT07014306 — The Oswestry Metabolic BONE Cohort · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05576064 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
- Last refreshed: 4 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05576064.
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