Last reviewed · How we verify
NCT04017793
Mindfulness-Associated Brain Changes in Adults With Autism
NA trial testing Mindfulness Based Stress Reduction in Autism Spectrum Disorder in 108 participants. Completed in 31 December 2024.
31 December 2021
Quick facts
| Lead sponsor | Arizona State University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 108 |
| Start date | 6 May 2019 |
| Primary completion | 31 December 2021 |
| Estimated completion | 31 December 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Mindfulness Based Stress Reduction
- Relaxation Group
Conditions studied
- Autism Spectrum Disorder — all drugs for Autism Spectrum Disorder →
Sponsor
Arizona State University
Who can join
18 and older, any sex, with Autism Spectrum Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study to measure brain functioning before and after stress-reduction classes to better understand how symptom improvements relate to brain functioning in adults with ASD (Autism Spectrum Disorder). Participants will be randomly assigned to one of two stress reduction classes that will meet once a week for 8 weeks. One group will complete a structured training program called Mindfulness Based Stress Reduction (MBSR) that involves teaching about increased mindfulness strategies and gentle stretching. The other group will review relaxation techniques and other stress reduction strategies and will include social support. Structural and functional MRI, EEG, and behavioral self-report data will be collected to understand more about how the brain changes in subtle ways when people feel better and are more aware of their emotional state.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Quality of life in adults with autism spectrum disorder: influence of age, sex, and a controlled, randomized mindfulness-based stress reduction pilot intervention.
Braden BB, Pagni BA, Monahan L, Walsh MJM, et al · · 2022 · cited 23× · PMID 34655389 · DOI 10.1007/s11136-021-03013-x -
Distinct and shared therapeutic neural mechanisms of mindfulness-based and social support stress reduction groups in adults with autism spectrum disorder.
Pagni BA, Hill E, Walsh MJM, Delaney S, et al · · 2023 · cited 7× · PMID 36990468 · DOI 10.1503/jpn.220159
Verify or expand the search:
- PubMed search for NCT04017793
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Mindfulness Based Stress Reduction
Trials testing the same drug.
- NCT04980612 — Development and Feasibility of Mindfulness Based Pain Reduction · NA · active not recruiting
- NCT05100537 — Effect of Mindfulness Based Stress Reduction (MBSR) Programme for Reducing the Stress Level of Nursing Student · NA · completed
- NCT05541263 — Mindful Network Dynamics Regulation Under Stress · NA · terminated
- NCT04016415 — Decreasing Stress in Diabetes · NA · completed
- NCT04625777 — Selah Trial of Stress Interventions for Clergy: Mindfulness Based Stress Reduction, Daily Examen, and Stress Inoculation · NA · completed
Other recruiting trials for Autism Spectrum Disorder
Currently open trials in the same condition.
- NCT07324057 — The Effects of Preoperative Intranasal Administration of Dexmedetomidine and Esketamine on Negative Postoperative Behavi · NA · recruiting
- NCT07493096 — Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disor · recruiting
- NCT07505290 — Efficacy of the Korean PEERS® for Preschoolers (PEERS®-PS-K) Social Skills Intervention: A Randomized Controlled Trial f · NA · active not recruiting
- NCT07524192 — A Self-Instructional Online Program for Early Childhood and Elementary Teachers Supporting Autistic Children and Childre · NA · recruiting
- NCT07432776 — Effect of an 8-Week Pickleball Program for Adults With Autism: A Feasibility Trial With a Delayed-Control Design · EARLY_PHASE1 · recruiting
Other Arizona State University trials
Trials by the same sponsor.
- NCT07519408 — Acute Kidney Injury and Ultra-endurance Running · NA · not yet recruiting
- NCT05784467 — Methamphetamine, PrEP, and Intersectional Stigma Study · NA · not yet recruiting
- NCT07375043 — Drumming Groups for Parents of Autistic Children · NA · not yet recruiting
- NCT07297901 — App-based Breathing Program for Migraine Relief · NA · enrolling by invitation
- NCT06721793 — The Impact of a Caffeinated Sports Drink on Performance · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04017793 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Arizona State University
- Last refreshed: 15 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04017793.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing