NCT04016623 is a NA clinical trial of 1-day toric test contact lens in Astigmatism, sponsored by CooperVision, Inc..

Who is sponsoring NCT04016623?

NCT04016623 is sponsored by CooperVision, Inc..

What drugs are being tested in NCT04016623?

Interventions in NCT04016623: 1-day toric test contact lens, 1-day toric control contact lens.

What condition does NCT04016623 study?

NCT04016623 studies Astigmatism.

Is NCT04016623 still recruiting?

NCT04016623 is currently completed. Last updated 14 August 2020.

Are results published for NCT04016623?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2020-08-14 · How we verify

NCT04016623

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Evaluation of Invigor Toric 1-Day Contact Lenses

Completed NA Results posted Last updated 14 August 2020

What this trial tests

NA trial testing 1-day toric test contact lens in Astigmatism in 10 participants. Completed in 4 June 2019.

Timeline

6 May 2019

Primary endpoint
15 May 2019

4 June 2019

Quick facts

Lead sponsor	CooperVision, Inc.
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	factorial
Masking	double
Primary purpose	treatment
Enrollment	10
Start date	6 May 2019
Primary completion	15 May 2019
Estimated completion	4 June 2019
Sites	1 location across United States

Drugs / interventions tested

1-day toric test contact lens
1-day toric control contact lens

Conditions studied

Astigmatism — all drugs for Astigmatism →

Sponsor

CooperVision, Inc.

Who can join

18 and older, any sex, with Astigmatism. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Visibility of Toric Mark Primary · 1 hour

Toric Mark visible or not visible. Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Visible

Group	Value	95% CI
Test Contact Lenses	100
Control Contact Lenses	100

Not Visible

Group	Value	95% CI
Test Contact Lenses	0
Control Contact Lenses	0

Degree of Lens Orientation Primary · Baseline

Average of lens toric mark mislocation from the resting toric mark away from the 6 o'clock position - measured in degrees. Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Group	Value	95% CI
Test Contact Lenses	0	± 7
Control Contact Lenses	-1	± 7

Degree of Lens Orientation Primary · 15 minutes

Average of lens toric mark mislocation from the resting toric mark away from the 6 o'clock position - measured in degrees. Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Group	Value	95% CI
Test Contact Lenses	1	± 6
Control Contact Lenses	0	± 7

Degree of Lens Orientation Primary · 1 hour

Average of lens toric mark mislocation from the resting toric mark away from the 6 o'clock position - measured in degrees. Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Group	Value	95% CI
Test Contact Lenses	-1	± 6
Control Contact Lenses	-1	± 6

Toric Stability Primary · 15 minutes

Toric stability (maximal and minimal differences between extreme gazes) measured in degrees for up, down, right, and left gazes. Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Group	Value	95% CI
Test Contact Lenses	4	± 3
Control Contact Lenses	4	± 3

Toric Stability Primary · 1 hour

Rotational stability (maximal and minimal differences between extreme gazes) measured in degrees for up, down, right, and left gazes. Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Group	Value	95% CI
Test Contact Lenses	5	± 3
Control Contact Lenses	4	± 3

Degree of Rotational Recovery Primary · 15 minutes

Rotational Recovery for nasal and temporal - measured in degrees. Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Nasal

Group	Value	95% CI
Test Contact Lenses	16	± 9
Control Contact Lenses	15	± 10

Temporal

Group	Value	95% CI
Test Contact Lenses	10	± 10
Control Contact Lenses	10	± 9

Degree of Rotational Recovery Primary · 1 hour

Rotational Recovery for nasal and temporal - measured in degrees. Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Nasal

Group	Value	95% CI
Test Contact Lenses	16	± 9
Control Contact Lenses	12	± 10

Temporal

Group	Value	95% CI
Test Contact Lenses	9	± 10
Control Contact Lenses	10	± 10

Toric Fit Acceptance Primary · 15 minutes

Toric fit acceptance and preference scale 0-4 (0 = can't be worn, 4 = optimum). Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Group	Value	95% CI
Test Contact Lenses	3.5	± 0.2
Control Contact Lens	3.4	± 0.2

Toric Fit Acceptance Primary · 1 hour

Toric fit acceptance and preference scale 0-4 (0 = can't be worn, 4 = optimum). Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Group	Value	95% CI
Test Contact Lenses	3.5	± 0.2
Control Contact Lenses	3.4	± 0.3

Toric Fit Preference Primary · Baseline

Investigator's toric fitting preference - Test lens , No Preference , Control lens. Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Test Lens

Group	Value	95% CI
Overall Study	23

No Preference

Group	Value	95% CI
Overall Study	69

Control Lens

Group	Value	95% CI
Overall Study	8

Toric Fit Preference Primary · 1 hour

Investigator's toric fitting preference - Test lens, No Preference, Control lens. Data for all 4 pairs were combined and analyzed (n=40 contact lenses).

Test Lens

Group	Value	95% CI
Overall Study	33

No Preference

Group	Value	95% CI
Overall Study	57

Control Lens

Group	Value	95% CI
Overall Study	10

Sponsor's own description

An evaluation of the clinical performance of the 1-day toric test contact lens compared to the 1-day toric control contact lens over one hour of lens wear.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Astigmatism

Currently open trials in the same condition.

NCT07303920 — Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day · NA · recruiting
NCT07284966 — Comfort and Vision With TOTAL30 Multifocal Lenses · recruiting
NCT07078799 — Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery · NA · recruiting
NCT07084844 — Patient Reported Outcomes With WaveLight Plus LASIK · recruiting
NCT07140653 — Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery · Phase 4 · recruiting

Other CooperVision, Inc. trials

Trials by the same sponsor.

NCT06817785 — Soft Lens Study: Biomedics 1 Day Extra Sphere and Clariti 1 Day Sphere · NA · completed
NCT06758076 — A Clinical Comparison of Two Soft Contact Lenses (C24-755) · NA · completed
NCT06590441 — Investigation of Wearing Compliance of Spectacles for Myopia Control · completed
NCT06609018 — Clinical Investigation of Buttermere (LENS 271) Soft Contact Lenses · NA · completed
NCT06611410 — 1 Week Crossover Study Between Two Soft Contact Lenses · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04016623 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by CooperVision, Inc.
Last refreshed: 14 August 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04016623.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing

NCT04016623

Quick facts

Drugs / interventions tested

Conditions studied

Sponsor

Who can join

Results — posted to ClinicalTrials.gov

Sponsor's own description

Publications & conference data

Related trials

Other recruiting trials for Astigmatism

Other CooperVision, Inc. trials

Verify against primary sources