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NCT04006717
Comparison Between Low-level Laser Therapy, Intracanal Cryotherapy and Their Combination, on Post-endodontic Pain Level
NA trial testing Low Level Laser therapy in Low-level Light Therapy in 95 participants. Completed in 1 November 2024.
1 June 2024
Quick facts
| Lead sponsor | Misr International University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 95 |
| Start date | 24 June 2019 |
| Primary completion | 1 June 2024 |
| Estimated completion | 1 November 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Low Level Laser therapy — full drug profile →
- Intra canal Cryotherapy
Conditions studied
- Low-level Light Therapy — all drugs for Low-level Light Therapy →
- Cryotherapy — all drugs for Cryotherapy →
Sponsor
Misr International University
Who can join
Adults 18 to 40, any sex, with Low-level Light Therapy or Cryotherapy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Statement of the problem: Postoperative pain following endodontic treatment is a common complication that might require analgesics for pain relief. Low-level laser therapy (LLLT) and Intracanal Cryotherapy (ICCT) are both recommended as non-pharmacological and non-invasive treatment modalities for management of painful situations. Aim of the study: This study is conducted to clinically evaluate and compare the effect of both LLLT and ICCT on post-endodontic pain (PEP) over 5 days in molars with symptomatic apical periodontitis (SAP) using visual analog scale (VAS). Materials \& Methods: This parallel arm, randomized clinical trial will involve 95 systemically free patients with SAP in molars. The patients will be randomly allocated to 5 equal groups as follows: control (no intervention), placebo (mock laser therapy), LLLT, ICCT and a combination of both. Postoperative pain levels after 6 hrs, 12 hrs, on 2nd day and 5th day are going to be assessed on the VAS and shall be noted. Data collected will be tabulated and statistically analysed.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04006717
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Low Level Laser therapy
Trials testing the same drug.
- NCT05550168 — Effect of Low-level Laser Therapy on Orthodontic Tooth Movement · NA · completed
Other Misr International University trials
Trials by the same sponsor.
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- NCT07006519 — The Prevalence of Incisal Angle of Maxillary Central Incisors in Adults · completed
- NCT06645925 — Novel Soft Tissue Augmentation Technique Using Free Gingival Graft Simultaneous With Posterior Mandibular Implant · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04006717 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Misr International University
- Last refreshed: 18 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04006717.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing