Last reviewed · How we verify
NCT06645925
Novel Soft Tissue Augmentation Technique Using Free Gingival Graft Simultaneous With Posterior Mandibular Implant
NA trial testing One Step Protocol in Free Gingival Graft in 22 participants. Currently enrolling.
30 November 2026
Quick facts
| Lead sponsor | Misr International University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 22 |
| Start date | 1 November 2025 |
| Primary completion | 30 November 2026 |
| Estimated completion | 30 December 2027 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- One Step Protocol
- Two Steps Protocol
Conditions studied
- Free Gingival Graft — all drugs for Free Gingival Graft →
- Free Gingival Graft Volume Change — all drugs for Free Gingival Graft Volume Change →
- Keratinized Tissue — all drugs for Keratinized Tissue →
Sponsor
Misr International University
Who can join
Adults 18 to 50, any sex, with Free Gingival Graft or Free Gingival Graft Volume Change. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Presence of keratinized tissue (KT) around dental implants, plays a crucial role in stability and health of peri-implant tissues. Several studies reported that, minimum of 2 mm keratinized tissue width is required to achieve long-term longevity. Insufficient keratinized mucosa leads to biofilm accumulation, soft tissue inflammation, eventually peri-implant mucositis and peri-implantitis. Hence, the aim of the present trial is to evaluate KTW gain, linear and volumetric changes in buccal soft tissue along with hard tissue alterations following implant restoration at sites treated either with delayed implant placement \& simultaneous FGG or the conventional FGG protocol prior to implant placement.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06645925
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Free Gingival Graft
Currently open trials in the same condition.
- NCT07019428 — Clinical Evaluation of a Modified Technique for Free Gingival Graft Stabilization Using Titanium Fixation Tacs Around Im · NA · recruiting
Other Misr International University trials
Trials by the same sponsor.
- NCT04466371 — Perceptions of Undergraduate Students and Teaching Staff on Online Teaching · suspended
- NCT06648135 — Labial Bone Thickness Around Immediate Implants in the Esthetic Zone Following a Novel Socket Evaluation System · not yet recruiting
- NCT07340606 — The Role of the Pre-operative Condition and Artificial Intelligence-Assisted Diagnosis in Predicting the Success of Full · NA · recruiting
- NCT07006519 — The Prevalence of Incisal Angle of Maxillary Central Incisors in Adults · completed
- NCT06207565 — Immediate Implant Placement Utilizing Vestibular Flap Versus Single Flap Approach With Bone Graft · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06645925 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Misr International University
- Last refreshed: 29 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06645925.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing